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II~TER-®FFICE MEMORANDU M
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Preliminary screening of several commercially available,'inexpen-
L,ive anion exchange resins has been carried out . The stronCly basic
macroreticular resins IRA-900, IRA-~910, and IRA-911 produced by Rohm and
Haas-Company as well as the intermediate base Duolite A-57 resin produced
by Diamond Shamrock Chemical Company have proved to be of no value for
enzyme binding .
.. .... . .
The weakly basic, macroreticular anion exchange resin IRA-9 3
by Rohm and Haas has been shown to possess considerable binding capacity
for glucose isomerase . The most probable reason for the .more effective
binding of IRA-93 over IRA-900 is the fact that the average pore diameter
of IRA-93 is twice as large as that of IRA-900, allowing the penetration
of the relatively large glucose isomerase molecule into the resin beads .
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