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(S)-(+)-2-(tert-Butyl)-3-methyl-4-imidazolidinone trifluoroacetic acid (CAS 900503-70-0)

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Alternate Names:
(S)-(+)-2-(tert-Butyl)-3-methyl-4-oxoimidazolidinium trifluoroacetate
CAS Number:
900503-70-0
Molecular Weight:
270.25
Molecular Formula:
C10H17N2O3F3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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(S)-(+)-2-(tert-Butyl)-3-methyl-4-imidazolidinone trifluoroacetic acid is a chemical compound that has garnered significant attention due to its potential applications in scientific research. It serves as a chiral auxiliary, playing a crucial role in various organic synthesis reactions aimed at enhancing yield and selectivity of target products. The mechanism of action involves the formation of a chiral complex between the compound and the reactants, leading to the formation of a single enantiomer of the product. Acting as a template, the chiral auxiliary guides the reaction, directing it towards the desired enantiomer of the final product.

References:

  1. New strategies in organic catalysis: the first enantioselective organocatalytic Friedel-Crafts alkylation.  |  Paras, NA. and MacMillan, DW. 2001. J Am Chem Soc. 123: 4370-1. PMID: 11457218