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ABCG2 Antibody (B-1): sc-377176
- ABCG2 Antibody (B-1) is a mouse monoclonal IgG1 κ ABCG2 antibody, cited in 41 publications, provided at 200 µg/ml
- raised against amino acids 301-370 mapping within an internal region of ABCG2 of human origin
- ABCG2 Antibody (B-1) is recommended for detection of ABCG2 of human origin by WB, IP, IF, IHC(P) and ELISA
- Anti-ABCG2 Antibody (B-1) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of ABCG2 (B-1): sc-377176.
- m-IgGκ BP-HRP is the preferred secondary detection reagent for ABCG2 Antibody (B-1) for WB and IHC(P) applications. This reagent is now offered in a bundle with ABCG2 Antibody (B-1) (see ordering information below). For additional m-IgGκ BP conjugates see our complete list of Mouse IgG Binding Proteins.
ABCG2 Antibody (B-1) is an IgG1 κ mouse monoclonal ABCG2 antibody (also designated CD338 antibody, or ATP binding cassette subfamily G member 2 antibody) that detects the ABCG2 protein of human origin by WB, IP, IF, IHC(P) and ELISA. ABCG2 Antibody (B-1) is available as both the non-conjugated anti-ABCG2 antibody form, as well as multiple conjugated forms of anti-ABCG2 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. ATP-binding cassette (ABC) transporters are an evolutionarily conserved family of proteins that catalyze the transport of molecules across extracellular and intracellular membranes through the energy of ATP hydrolysis. The ABC half-transporter, ABCG2, is also known as placenta-specific ABC transporter and breast cancer resistance protein (BCRP1). ABCG2 confers resistance for a variety of chemotherapeutic agents, including anthracyclines, mitoxantrone, bisantrene and topotecan. Under normal conditions, ABCG2 may serve a protective function by removing toxins from the cell, and plays an important role in regulating stem cell differentiation. ABCG2 is responsible for the side population (SP) phenotype and is widely expressed in a large variety of stem cells, making it an important stem cell marker. ABCG2 may have N-linked glycosylation and may dimerize in vivo. ABCG2 is abundantly expressed in placenta, liver, intestine and stem cells.
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