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... 900098 is a simple very polar compound making it an unsuitable candidate for routine reverse phase HPLC. However, it possesses ionizable functional groups in its structure (Figure 1) making it suitable for HPCE. Thus we prioritize in developing an HPCE analytical method for this molecule than HPLC. ...
Context 2
... 900098 is an antimalarial compound in development showing promising activity in vitro and in vivo. It belongs to the class of fosmidomycin antimalarial compounds. Chemically it is a methyl derivative of fosmidomycin as shown in Figure 1. It has antimalarial activity twice more than the parent compound fosmidomycin with an IC 50 value ranging from 70-180 nM in different strains of Plasmodium falciparum ...
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