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Hydrocephalus in myelomeningocele

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Abstract

Purpose

To investigate certain aspects of hydrocephalus in patients with myelomeningocele.

Methods

We retrospectively analyzed data of 1050 patients with myelomeningocele who underwent surgical treatment between June 1991 and June 2021. These patients were divided into three groups: group 1 consisted of patients who underwent surgery after the first 6 h of life, group 2 consisted of patients who underwent surgery within the first 6 h, and group 3 consisted of patients who underwent surgery during the fetal period and before 26 6/7 weeks of gestation.

Results

There were 125, 590, and 335 patients in groups 1, 2, and 3, respectively. In groups 1 and 2, 593 (83%) patients developed hydrocephalus after birth and required ventriculoperitoneal shunt placement in the maternity ward, mainly within the first 4 days of life. In contrast, in group 3, 24 (7.2%) patients required surgery to treat hydrocephalus after birth. Hydrocephalus was the primary cause of mortality in groups 1 and 2, with mortality rates of 35% and 10%, respectively. In group 3, the mortality rate was 0.8% and was not related to hydrocephalus.

Conclusion

The onset of hydrocephalus is directly related to myelomeningocele closure in neurosurgery.

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Authors and Affiliations

  1. Department Neurology and Neurosurgery, Universidade Federal de Sao Paulo, Rua Napoleão de Barros, 715, 6th Floor, Sao Paulo, SP, 04024-002, Brazil

    Sergio Cavalheiro, Marcos Devanir Silva da Costa, Patricia Alessandra Dastoli & Jardel Nicácio Mendonça

  2. Department of Fetal Medicine, Hospital E Maternidade Santa Joana, São Paulo, SP, Brazil

    Mauricio Mendes Barbosa & Antonio Fernandes Moron

  3. Department of Fetal Neurosurgery, Hospital e Maternidade Santa Joana, São Paulo, SP, Brazil

    Sergio Cavalheiro, Marcos Devanir Silva da Costa, Patricia Alessandra Dastoli & Jardel Nicácio Mendonça

  4. Faculdade de Medicina de Jundiaí, Jundiai, SP, Brazil

    Daniela Cavalheiro

  5. Department of Obstetrics, Faculdade de Medicina Einstein, São Paulo, SP, Brazil

    Mauricio Mendes Barbosa

Authors
  1. Sergio Cavalheiro
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  2. Marcos Devanir Silva da Costa
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  3. Mauricio Mendes Barbosa
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  4. Patricia Alessandra Dastoli
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  5. Jardel Nicácio Mendonça
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  6. Daniela Cavalheiro
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  7. Antonio Fernandes Moron
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Corresponding author

Correspondence to Marcos Devanir Silva da Costa.

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Ethics approval

The study was approved by the Research Ethics Committee of Universidade Federal de São Paulo, São Paulo, Brazil, under opinion number 2461706 (CAAE 79580517.6.0000.5505) on January 08, 2018. The requirement for informed consent was waived owing to the retrospective nature of the study.

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Cavalheiro, S., da Costa, M.D.S., Barbosa, M.M. et al. Hydrocephalus in myelomeningocele. Childs Nerv Syst 37, 3407–3415 (2021). https://doi.org/10.1007/s00381-021-05333-2

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