List of Publications and Acknowledgements 2006-2012 - McGill ...

McGill University and Génome Québec Innovation Centre 

Articles arising from research/collaborations or 

through services provided to others. 

Summary table 

Authorship and 

Co-authorship 

(Section A) 

Acknowledgements 

(Section B) 

2006 37 ND 

2007 56 32 

2008 48 72 

2009 64 88 

2010 90 81 

2011 175 104 

2012 177 115 

A) Co-authors 

2012 

1. Jacquemin B, Kauffmann F, Pin I, Le Moual N, Bousquet J, Gormand F, Just J,Nadif R, Pison C, 

Vervloet D, Künzli N, Siroux V; Epidemiological study on the Genetics and Environment of 

Asthma (EGEA). Air pollution and asthma control in the Epidemiological study on the Genetics 

and Environment of Asthma. J Epidemiol Community Health. 2012 Sep;66(9):796-802 (Lathrop, 

M.) 

2. Eyre S, Bowes J, Diogo D, Lee A, Barton A, Martin P, Zhernakova A, Stahl E,Viatte S, McAllister 

K, Amos CI, Padyukov L, Toes RE, Huizinga TW, Wijmenga C,Trynka G, Franke L, Westra HJ, 

Alfredsson L, Hu X, Sandor C, de Bakker PI, Davila S, Khor CC, Heng KK, Andrews R, Edkins S, 

Hunt SE, Langford C, Symmons D;Biologics in Rheumatoid Arthritis Genetics and Genomics 

Study Syndicate; Wellcome Trust Case Control Consortium, Concannon P, Onengut-Gumuscu S, 

Rich SS, Deloukas P, Gonzalez-Gay MA, Rodriguez-Rodriguez L, Ärlsetig L, Martin J,Rantapää- 

Dahlqvist S, Plenge RM, Raychaudhuri S, Klareskog L, Gregersen PK, Worthington J. Highdensity 

genetic mapping identifies new susceptibility loci for rheumatoid arthritis. Nat Genet. 2012 

Dec;44(12):1336-40 (Lathrop, M.) 

3. Jostins L, Ripke S, Weersma RK, Duerr RH, McGovern DP, Hui KY, Lee JC, Schumm LP, 

Sharma Y, Anderson CA, Essers J, Mitrovic M, Ning K, Cleynen I, Theatre E,Spain SL, 

Raychaudhuri S, Goyette P, Wei Z, Abraham C, Achkar JP, Ahmad T,Amininejad L, 

Ananthakrishnan AN, Andersen V, Andrews JM, Baidoo L, Balschun T,Bampton PA, Bitton A, 

Boucher G, Brand S, Büning C, Cohain A, Cichon S, D'Amato M, De Jong D, Devaney KL, 

Dubinsky M, Edwards C, Ellinghaus D, Ferguson LR,Franchimont D, Fransen K, Gearry R, 

Georges M, Gieger C, Glas J, Haritunians T,Hart A, Hawkey C, Hedl M, Hu X, Karlsen TH, 

Last verification: January 21 st 2013

Kupcinskas L, Kugathasan S, Latiano A, Laukens D, Lawrance IC, Lees CW, Louis E, Mahy G, 

Mansfield J, Morgan AR,Mowat C, Newman W, Palmieri O, Ponsioen CY, Potocnik U, Prescott 

NJ, Regueiro M, Rotter JI, Russell RK, Sanderson JD, Sans M, Satsangi J, Schreiber S, Simms 

LA,Sventoraityte J, Targan SR, Taylor KD, Tremelling M, Verspaget HW, De Vos M,Wijmenga C, 

Wilson DC, Winkelmann J, Xavier RJ, Zeissig S, Zhang B, Zhang CK,Zhao H; International IBD 

Genetics Consortium (IIBDGC), Silverberg MS, Annese V, Hakonarson H, Brant SR, Radford- 

Smith G, Mathew CG, Rioux JD, Schadt EE, Daly MJ,Franke A, Parkes M, Vermeire S, Barrett 

JC, Cho JH. Host-microbe interactions have shaped the genetic architecture of inflammatory 

bowel disease. Nature. 2012 Nov 1;491(7422):119-24 (Lathrop, M) 

4. Cooper JD, Simmonds MJ, Walker NM, Burren O, Brand OJ, Guo H, Wallace C,Stevens H, 

Coleman G; Wellcome Trust Case Control Consortium, Franklyn JA, Todd JA, Gough SC. Seven 

newly identified loci for autoimmune thyroid disease. Hum Mol Genet. 2012 Dec 1;21(23):5202-8. 

(Lathrop, M) 

5. Clarke L, Zheng-Bradley X, Smith R, Kulesha E, Xiao C, Toneva I, Vaughan B,Preuss D, 

Leinonen R, Shumway M, Sherry S, Flicek P; 1000 Genomes Project Consortium. The 1000 

Genomes Project: data management and community access. Nat Methods. 2012 Apr 

27;9(5):459-62. (Lathrop, M) 

6. Stein JL, Medland SE, Vasquez AA, Hibar DP, Senstad RE, Winkler AM, Toro R,Appel K, 

Bartecek R, Bergmann Ø, Bernard M, Brown AA, Cannon DM, Chakravarty MM, Christoforou A, 

Domin M, Grimm O, Hollinshead M, Holmes AJ, Homuth G, Hottenga JJ, Langan C, Lopez LM, 

Hansell NK, Hwang KS, Kim S, Laje G, Lee PH, Liu X, Loth E, Lourdusamy A, Mattingsdal M, 

Mohnke S, Maniega SM, Nho K, Nugent AC, O'Brien C, Papmeyer M, Pütz B, Ramasamy A, 

Rasmussen J, Rijpkema M, Risacher SL, Roddey JC, Rose EJ, Ryten M, Shen L, Sprooten E, 

Strengman E, Teumer A, Trabzuni D,Turner J, van Eijk K, van Erp TG, van Tol MJ, Wittfeld K, 

Wolf C, Woudstra S,Aleman A, Alhusaini S, Almasy L, Binder EB, Brohawn DG, Cantor RM, 

Carless MA, Corvin A, Czisch M, Curran JE, Davies G, de Almeida MA, Delanty N, Depondt C, 

Duggirala R, Dyer TD, Erk S, Fagerness J, Fox PT, Freimer NB, Gill M, Göring HH, Hagler DJ, 

Hoehn D, Holsboer F, Hoogman M, Hosten N, Jahanshad N, Johnson MP,Kasperaviciute D, Kent 

JW Jr, Kochunov P, Lancaster JL, Lawrie SM, Liewald DC, Mandl R, Matarin M, Mattheisen M, 

Meisenzahl E, Melle I, Moses EK, Mühleisen TW, Nauck M, Nöthen MM, Olvera RL, Pandolfo M, 

Pike GB, Puls R, Reinvang I, Rentería ME, Rietschel M, Roffman JL, Royle NA, Rujescu D, 

Savitz J, Schnack HG, Schnell K, Seiferth N, Smith C, Steen VM, Valdés Hernández MC, Van 

den Heuvel M, van der Wee NJ, Van Haren NE, Veltman JA, Völzke H, Walker R, Westlye LT, 

Whelan CD, Agartz I, Boomsma DI, Cavalleri GL, Dale AM, Djurovic S, Drevets WC, Hagoort P, 

Hall J, Heinz A, Jack CR Jr, Foroud TM, Le Hellard S, Macciardi F, Montgomery GW, Poline JB, 

Porteous DJ, Sisodiya SM, Starr JM, Sussmann J, Toga AW, Veltman DJ, Walter H, Weiner MW; 

Alzheimer's Disease Neuroimaging Initiative; EPIGEN Consortium; IMAGEN Consortium; 

Saguenay Youth Study Group, Bis JC, Ikram MA,Smith AV, Gudnason V, Tzourio C, Vernooij 

MW, Launer LJ, DeCarli C, Seshadri S;Cohorts for Heart and Aging Research in Genomic 

Epidemiology Consortium,Andreassen OA, Apostolova LG, Bastin ME, Blangero J, Brunner HG, 

Buckner RL,Cichon S, Coppola G, de Zubicaray GI, Deary IJ, Donohoe G, de Geus EJ, Espeseth 

T, Fernández G, Glahn DC, Grabe HJ, Hardy J, Hulshoff Pol HE, Jenkinson M, Kahn RS, 

McDonald C, McIntosh AM, McMahon FJ, McMahon KL, Meyer-Lindenberg A, Morris DW, Müller- 

Myhsok B, Nichols TE, Ophoff RA, Paus T, Pausova Z, Penninx BW, Potkin SG, Sämann 

PG,Saykin AJ, Schumann G, Smoller JW, Wardlaw JM, Weale ME, Martin NG, Franke B, Wright 

MJ, Thompson PM; Enhancing Neuro Imaging Genetics through. Meta-Analysis Consortium. 

Identification of common variants associated with human hippocampal and intracranial volumes. 

Nat Genet. 2012 Apr 15;44(5):552-61(Lathrop, M) 

7. Ghassibe-Sabbagh M, Platt DE, Youhanna S, Abchee AB, Stewart K, Badro DA,Haber M, 

Salloum AK, Douaihy B, el Bayeh H, Othman R, Shasha N, Kibbani S,Chammas E, Milane A, 

Nemr R, Kamatani Y, Hager J, Cazier JB, Gauguier D, Zalloua PA; FGENTCARD Consortium. 

Genetic and environmental influences on total plasma homocysteine and its role in coronary 

artery disease risk. Atherosclerosis. 2012 May;222(1):180-6 (Lathrop, M)Almlöf JC, Lundmark P, 

Lundmark A, Ge B, Maouche S, Göring HH, Liljedahl U, Enström C, Brocheton J, Proust C, 

Godefroy T, Sambrook JG, Jolley J, Crisp-Hihn A, Foad N, Lloyd-Jones H, Stephens J, Gwilliam 

R, Rice CM, Hengstenberg C, Samani NJ, Erdmann J, Schunkert H, Pastinen T, Deloukas P, 


Goodall AH, Ouwehand WH, Cambien F, Syvänen AC. “Powerful Identification of Cis-regulatory 

SNPs in Human Primary Monocytes Using Allele-Specific Gene Expression”. PLoS One. 

2012;7(12):e52260. PMID:23300628. 

8. Angelakopoulou A, Shah T, Sofat R, Shah S, Berry DJ, Cooper J, Palmen J, Tzoulaki I, Wong A, 

Jefferis BJ, Maniatis N, Drenos F, Gigante B, Hardy R, Laxton RC, Leander K, Motterle A, 

Simpson IA, Smeeth L, Thomson A, Verzilli C, Kuh D, Ireland H, Deanfield J, Caulfield M, 

Wallace C, Samani N, Munroe PB, Lathrop M, Fowkes FG, Marmot M, Whincup PH, Whittaker 

JC, de Faire U, Kivimaki M, Kumari M, Hypponen E, Power C, Humphries SE, Talmud PJ, Price 

J, Morris RW, Ye S, Casas JP, Hingorani AD. Comparative analysis of genome-wide association 

studies signals for lipids, diabetes, and coronary heart disease: Cardiovascular Biomarker 

Genetics Collaboration. Eur Heart J. 2012 Feb;33(3):393-407. 

9. Bard-Chapeau EA, Jeyakani J, Kok CH, Muller J, Chua BQ, Gunaratne J, Batagov A, 

Jenjaroenpun P, Kuznetsov VA, Wei CL, D'Andrea RJ, Bourque G, Jenkins NA, Copeland NG. 

“Ecotopic viral integration site 1 (EVI1) regulates multiple cellular processes important for cancer 

and is a synergistic partner for FOS protein in invasive tumors”. Proc Natl Acad Sci U S A. 2012 

Feb 7;109(6):2168-73. PMID: 22308434 

10. Beauchemin M, Roy S, Daoust P, Dagenais-Bellefeuille S, Bertomeu T, Letourneau L, Franz 

Lang B, Morse D. Dinoflagellate tandem array gene transcripts are highly conserved and not 

polycistronic. PNAS - September 25, 2012, vol. 109, no. 39, 15793–15798. 

11. Beaulieu YB, Kleinman CL, Landry-Voyer AM, Majewski J, Bachand F. “Polyadenylationdependent 

control of long noncoding RNA expression by the poly(A)-binding protein nuclear 1”. 

PLoS Genet. 2012 Nov;8(11):e1003078. PMID: 23166521 

12. Berlivet S, Moussette S, Ouimet M, Verlaan DJ, Koka V, Al Tuwaijri A, Kwan T, Sinnett 

D,·Pastinen T, Naumova AK. Interaction between genetic and epigenetic variation deWnes gene 

expression patterns at the asthma-associated locus 17q12-q21 in lymphoblastoid cell lines. Hum 

Genet (2012) 131:1161–1171. DOI 10.1007/s00439-012-1142-x. 

13. Bernier FP, Caluseriu O, Ng S, Schwartzentruber J, Buckingham KJ, Innes AM, Jabs EW, Innis 

JW, Schuette JL, Gorski JL, Byers PH, Andelfinger G, Siu V, Lauzon J, Fernandez BA, McMillin 

M, Scott RH, Racher H, FORGE Canada Consortium, Majewski J, Nickerson DA, Shendure J, 

Bamshad MJ, and Parboosingh JS. Haploinsufficiency of SF3B4, a Component of the Pre-mRNA 

Spliceosomal Complex, Causes Nager Syndrome. May 2012. AJHG. Volume 90, Issue 5 – 

Pages 925-933. 

14. Berryer MH, Hamdan FF, Klitten LL, Møller RS, Carmant L, Schwartzentruber J, Patry L, 

Dobrzeniecka S, Rochefort D, Neugnot-Cerioli M, Lacaille JC, Niu Z, Eng CM, Yang Y, Palardy S, 

Belhumeur C, Rouleau GQ, Tommerup N, Immken L, Beauchamp MH,1 Patel GS, Majewski J, 

Tarnopolsky MA, Scheffzek K, Hjalgrim H, Michaud JL, and Di Cristo G. Mutations in SYNGAP1 

Cause Intellectual Disability, Autism, and a Specific Form of Epilepsy by Inducing 

Haploinsufficiency. Human Mutation, Vol. 00, No. 0, 1–9, 2012. 

15. Billings LK, Hsu YH, Ackerman RJ, Dupuis J, Voight BF, Rasmussen-Torvik LJ, Hercberg S, 

Lathrop M, Barnes D, Langenberg C, Hui J, Fu M, Bouatia-Naji N, Lecoeur C, An P, Magnusson 

PK, Surakka I, Ripatti S, Christiansen L, Dalgård C, Folkersen L, Grundberg E; the MAGIC 

Investigators; the DIAGRAM + Consortium; the MuTHER Consortium; the ASCOT Investigators; 

the GEFOS Consortium, Eriksson P, Kaprio J, Ohm Kyvik K, Pedersen NL, Borecki IB, Province 

MA, Balkau B, Froguel P, Shuldiner AR, Palmer LJ, Wareham N, Meneton P, Johnson T, Pankow 

JS, Karasik D, Meigs JB, Kiel DP, Florez JC. Impact of Common Variation in Bone-Related 

Genes on Type 2 Diabetes and Related Traits. Diabetes. 2012 Aug;61(8):2176-2186 

16. Bing X, Zhang J, Sinclair BJ. A comparison of Frost expression among species and life stages of 

Drosophila. (2012) Insect Molecular Biology 21(1), 31–39. 

17. Boivin GA, Pothlichet J, Skamene E, Brown EG, Loredo-Osti JC, Sladek R, Vidal SM. Mapping 

of Clinical and Expression Quantitative Trait Loci in a Sex-Dependent Effect of Host Susceptibility 

to Mouse-Adapted Influenza H3N2/HK/1/68. J Immunol 2012; 188:3949-3960. 


18. Bombard Y, Miller FA, Hayeems RZ, Carroll JC, Avard D, Wilson BJ, Little J, Bytautas JP, 

Allanson J, Axler R, Giguere Y, Chakraborty P. Citizens' Values Regarding Research with Stored 

Samples from Newborn Screening in Canada. (2012) 129:2 Official Journal of the American 

Academy of Pediatrics, p.239. 

19. Bongfen SE, Rodrigue-Gervais IG, Berghout J, Torre S, Cingolani P, Wiltshire SA, Leiva-Torres 

GA, Letourneau L, Sladek R, Blanchette M, Lathrop M, Behr MA, Gruenheid S, Vidal SM, 

Saleh M, Gros P. 2012. An N-ethyl-N-nitrosourea (ENU)-induced dominant negative mutation in 

the JAK3 kinase protects against cerebral malaria. 

20. Bonnefond A, Clément N, Fawcett K, Yengo L, Vaillant E, Guillaume J-L, Dechaume A, Payne F, 

Roussel R, Czernichow S, Hercberg S, Hadjadj S, Balkau B, Marre M, Lantieri O, Langenberg C, 

Bouatia-Naji N, The Meta-Analysis of Glucose and Insulin-Related Traits Consortium (MAGIC), 

Charpentier G, Vaxillaire M, Rocheleau G, Wareham NJ, Sladek R, McCarthy MI, Dina C, 

Barroso I, Jockers R & Froguel P. Rare MTNR1B variants impairing melatonin receptor 1B 

function contribute to type 2 diabetes. Nature Genetics - Volume: 44, Pages: 297–301(2012). 

doi:10.1038/ng.1053. 

21. Botla SK, Gholami AM, Malekpour M, Moskalev EA, Fallah M, Jandaghi P, Aghajani A, Bondar 

IS, Omranipour R, Malekpour F, Mohajeri A, Babadi AJ, Sahin O, Bubnov VV, Najmabadi H, 

Hoheisel JD, Riazalhosseini Y. Diagnostic values of GHSR DNA methylation pattern in breast 

cancer. Breast Cancer Res Treat. DOI 10.1007/s10549-012-2197-z. 

22. Bouzigon E, Monier F, Boussaha M, Le Moual N, Huyvaert H, Matran R, Letort S, Bousquet J, 

Pin I, Lathrop M, Kauffmann F, Demenais F, Nadif R; EGEA Cooperative Group. Associations 

between nitric oxide synthase genes and exhaled NO-related phenotypes according to asthma 

status. PLoS One. 2012;7(5):e36672 

23. Budin-Ljøsne I, Harris JR, Kaye J, Knoppers BM, Tassé AM, Bravo E, Cambon-Thomsen A, 

Eriksson M, Kyvik KO, Litton J-E, Perola M, Rial-Sebbag E. ELSI challenges and strategies of 

national biobanks infrastructures. (2012) 21:2 Norwegian Journal of Epidemiology, p. 155. 

24. Campeau PM, Kim JC, Lu JT, Schwartzentruber JA, Abdul-Rahman OA, Schlaubitz S, Murdock 

DM, Jiang M-M, Lammer EJ, Enns GM, Rhead WJ, Rowland J, Robertson SP, Cormier-Daire V, 

Bainbridge MN, Yang X-J, Gingras M-C, Gibbs RA, Rosenblatt DS, Majewski J, Lee BH. 

Mutations in KAT6B, Encoding a Histone Acetyltransferase, Cause Genitopatellar Syndrome. 

AJHG. Volume 90, Issue 2, February 2012, Pages 282-289. 

25. Cingolani P, Patel VM, Coon M, Nguyen T, Land SJ, Ruden DM, and Lu X. Using Drosophila 

melanogaster as a Model for Genotoxic Chemical Mutational Studies with a New Program, 

SnpSift. Front Genet. 2012; 3: 35. doi: 10.3389/fgene.2012.00035. 

26. Cipriani V, Leung HT, Plagnol V, Bunce C, Khan JC, Shahid H, Moore AT, Harding SP, Bishop 

PN, Hayward C, Campbell S, Armbrecht AM, Dhillon B, Deary IJ, Campbell H, Dunlop M, 

Dominiczak AF, Mann SS, Jenkins SA, Webster AR, Bird AC, Lathrop M, Zelenika D, Souied 

EH, Sahel JA, Léveillard T; French AMD Investigators, Cree AJ, Gibson J, Ennis S, Lotery AJ, 

Wright AF, Clayton DG, Yates JR. Genome-wide association study of age-related macular 

degeneration identifies associated variants in the TNXB-FKBPL-NOTCH4 region of chromosome 

6p21.3. Hum Mol Genet. 2012 Sep 15;21(18):4138-50 

27. Clarke R, Bennett DA, Parish S, Verhoef P, Dötsch-Klerk M, Lathrop M, Xu P, Nordestgaard BG, 

Holm H, Hopewell JC, Saleheen D, Tanaka T, Anand SS, Chambers JC, Kleber ME, Ouwehand 

WH, Yamada Y, Elbers C, Peters B, Stewart AF, Reilly MM, Thorand B, Yusuf S, Engert JC, 

Assimes TL, Kooner J, Danesh J, Watkins H, Samani NJ, Collins R, Peto R; MTHFR Studies 

Collaborative Group. Homocysteine and coronary heart disease: meta-analysis of MTHFR casecontrol 

studies, avoiding publication bias. PLoS Med. 2012 Feb;9(2):e1001177. 

28. Coelho D, Kim JC, Miousse IR, Fung S, du Moulin M, Buers I, Suormala T, Burda P, Frapolli M, 

Stucki M, Nürnberg P, Thiele H, Robenek H, Höhne W, Longo N, Pasquali M, Mengel E, Watkins 

D, Shoubridge EA, Majewski J, Rosenblatt DS, Fowler B, Rutsch F, Baumgartner MR. 2012. 


Mutations in ABCD4 cause a new inborn error of vitamin B(12) metabolism. Nat Genet. 2012 Aug 

26. doi: 10.1038/ng.2386. [Epub ahead of print] 

29. Dandara C, Adebamowo C, de Vries J, Dove ES, Fisher E, Gibbs RA, Hotez PJ, Kickbusch I, 

Knoppers BM, Masellis M, Oestergaard MZ, Pang T, Rotimi CN. An Idea Whose Time Has 

Come? An African Foresight Observatory on Genomics Medicine and Data-Intensive Global 

Science. (2012) 10:1 Current Pharmacogenomics and Personalized Medicine, 7-15. 

30. Dastani Z, Hivert MF, Timpson N, Perry JR, Yuan X, Scott RA, Henneman P, Heid IM, Kizer JR, 

Lyytikäinen LP, Fuchsberger C, Tanaka T, Morris AP, Small K, Isaacs A, Beekman M, Coassin S, 

Lohman K, Qi L, Kanoni S, Pankow JS, Uh HW, Wu Y, Bidulescu A, Rasmussen-Torvik LJ, 

Greenwood CM, Ladouceur M, Grimsby J, Manning AK, Liu CT, Kooner J, Mooser VE, 

Vollenweider P, Kapur KA, Chambers J, Wareham NJ, Langenberg C, Frants R, Willems-Vandijk 

K, Oostra BA, Willems SM, Lamina C, Winkler TW, Psaty BM, Tracy RP, Brody J, Chen I, Viikari 

J, Kähönen M, Pramstaller PP, Evans DM, St Pourcain B, Sattar N, Wood AR, Bandinelli S, 

Carlson OD, Egan JM, Böhringer S, van Heemst D, Kedenko L, Kristiansson K, Nuotio ML, Loo 

BM, Harris T, Garcia M, Kanaya A, Haun M, Klopp N, Wichmann HE, Deloukas P, Katsareli E, 

Couper DJ, Duncan BB, Kloppenburg M, Adair LS, Borja JB; DIAGRAM+ Consortium; MAGIC 

Consortium; GLGC Investigators; MuTHER Consortium, Wilson JG, Musani S, Guo X, Johnson 

T, Semple R, Teslovich TM, Allison MA, Redline S, Buxbaum SG, Mohlke KL, Meulenbelt I, 

Ballantyne CM, Dedoussis GV, Hu FB, Liu Y, Paulweber B, Spector TD, Slagboom PE, Ferrucci 

L, Jula A, Perola M, Raitakari O, Florez JC, Salomaa V, Eriksson JG, Frayling TM, Hicks AA, 

Lehtimäki T, Smith GD, Siscovick DS, Kronenberg F, van Duijn C, Loos RJ, Waterworth DM, 

Meigs JB, Dupuis J, Richards JB, DIAGRAM Consortium; GIANT Consortium; Global B Pgen 

Consortium. 2012. Novel loci for adiponectin levels and their influence on type 2 diabetes and 

metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals. PLoS Genet. 

2012;8(3):e1002607. Epub 2012 Mar 29. 

31. Demirkan A, van Duijn CM, Ugocsai P, Isaacs A, Pramstaller PP, Liebisch G, Wilson JF, 

Johansson Å, Rudan I, Aulchenko YS, Kirichenko AV, Janssens AC, Jansen RC, Gnewuch C, 

Domingues FS, Pattaro C, Wild SH, Jonasson I, Polasek O, Zorkoltseva IV, Hofman A, Karssen 

LC, Struchalin M, Floyd J, Igl W, Biloglav Z, Broer L, Pfeufer A, Pichler I, Campbell S, Zaboli G, 

Kolcic I, Rivadeneira F, Huffman J, Hastie ND, Uitterlinden A, Franke L, Franklin CS, Vitart V; 

DIAGRAM Consortium, Nelson CP, Preuss M; CARDIoGRAM Consortium, Bis JC, O'Donnell 

CJ, Franceschini N; CHARGE Consortium, Witteman JC, Axenovich T, Oostra BA, Meitinger T, 

Hicks AA, Hayward C, Wright AF, Gyllensten U, Campbell H, Schmitz G; EUROSPAN 

consortium. 2012. Genome-wide association study identifies novel loci associated with circulating 

phospho- and sphingolipid concentrations. PLoS Genet 8:e1002490. 

32. Dizier MH, Etain B, Lajnef M, Lathrop M, Grozeva D, Craddock N, Henry C, Gard S, Jamain S, 

Leboyer M, Bellivier F, Mathieu F. Genetic heterogeneity according to age at onset in bipolar 

disorder: A combined positional cloning and candidate gene approach. Am J Med Genet B 

Neuropsychiatr Genet. 2012 Sep;159B(6):653-9. doi: 10.1002/ajmg.b.32069. 

33. Dizier MH, Margaritte-Jeannin P, Madore AM, Esparza-Gordillo J, Moffatt M, Corda E, Monier F, 

Guilloud-Bataille M, Franke A, Weidinger S, Annesi-Maesano I, Just J, Pin I, Kauffmann F, 

Cookson W, Lee YA, Laprise C, Lathrop M, Bouzigon E, Demenais F. The ANO3/MUC15 locus 

is associated with eczema in families ascertained through asthma. J Allergy Clin Immunol. 2012 

Jun;129(6):1547-53.e3. 

34. Dove ES, Joly Y. The Contested Futures of Biobanks and Intellectual Property. (2012) 11:1 

Teoria & derecho: revista de pensamiento juridico (Theory & Law: Journal of Legal Thought) 132- 

146. 

35. Dove ES, Joly Y, Knoppers BM. Power to the people: a wiki-governance model for biobanks. 

(2012) 13:5 Genome Bioliogy: 158. 

36. Dove ES, Ozdemir V. 'Regular science' is inherently political.. (2012) 13:12 EMBO Reports 

(Science and Society) doi:10.1038/embor.2012.205. 


37. Dove ES, Ozdemir V, Joly Y. Harnessing Omics Sciences, Population Databases, and Open 

Innovation Models for Theranostics-Guided Drug Discovery and Development. (2012) Drug 

Development Research DOI: 10.1002/ddr.21035. 

38. Dove ES, Faraj SA, Kolker E, Ozdemir V. Designing a post-genomics knowledge ecosystem to 

translate pharmacogenomics to public health action. (2012) Genome Medicine. 

39. Dragiev P, Nadon R, and Makarenkov V. Two effective methods for correcting experimental 

high-throughput screening data. Bioinformatics (2012) 28 (13): 1775-1782. doi: 

10.1093/bioinformatics/bts262. 

40. Durkin K, Coppieters W, Drögemüller C, Ahariz N, Cambisano N, Druet T, Fasquelle C, Haile A, 

Horin P, Huang L, Kamatani Y, Karim L, Lathrop M, Moser S, Oldenbroek K, Rieder S, Sartelet 

A, Sölkner J, Stålhammar H, Zelenika D, Zhang Z, Leeb T, Georges M, Charlier C. Serial 

translocation by means of circular intermediates underlies colour sidedness in cattle. Nature. 

2012 Feb 1;482(7383):81-4. doi: 10.1038/nature10757. 

41. Dyment DA, Cader MZ, Chao MJ, Morrison KM, Disanto G, Morahan JM, De Luca GC, 

Sadovnick AD, Lepage P, Montpetit A, Ebers GC, Ramagopalan SV. Exome sequencing 

identifies a novel multiple sclerosis susceptibility variant in the TYK2 gene. Neurology July 31, 

2012 vol. 79 no. 5 406-411. 

42. Ekström L, Gök E, Johansson M, Garle M, Rane A, Schulze J.J. Doping and Genetic Testing: 

Sex Difference in UGT2B15 Expression, Testosterone Glucuronidation Activity and Urinary 

Testosterone/Epitestosterone Glucuronide Ratio. (2012) 10: 2 Current Pharmacogenomics and 

Personalized Medicine 138. 

43. El-Sayed Moustafa JS, Eleftherohorinou H, de Smith AJ, Andersson-Assarsson JC, Couto Alves 

A, Hadjigeorgiou E, Walters RG, Asher JE, Bottolo L, Buxton JL, Sladek R, Meyre D, Dina C, 

Visvikis-Siest S, Jacobson P, Sjöström L, Carlsson LM, Walley A, Falchi M, Froguel P, Blakemore 

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Chamber and microfluidic probe for microperfusion of organotypic brain slices. Lab Chip 10: 326-334. 

71. Perrault CM, Qasaimeh MA, Brastaviceanu T, Anderson K, Kabakibo Y. Juncker D. 2010. Integrated 

microfluidic probe station. Review of Scientific Instruments. 81(11):115107-8. 

72. Safavieh R, Pla Roca M, Qasaimeh MA, Mirzaei M, Juncker D. 2010. Straight SU-8 pins. Journal of 

Micromechanics and Microengineering. 20(5). 

Ethics 

73. Wolfson M, Wallace SE, Masca N, Rowe G, Sheehan NA, Ferretti V, LaFlamme P, Tobin MD, 

Macleod J, Little J, Fortier I, Knoppers BM, Burton PR. 2010. DataSHIELD: resolving a conflict in 

contemporary bioscience--performing a pooled analysis of individual-level data without sharing the 

data. Int J Epidemiol. 2010 Oct;39(5):1372-82. Epub 2010 Jul 14. 

74. Howard HC, Knoppers BM, Borry P. 2010. Blurring lines. The research activities of direct-toconsumer 

genetic testing companies raise questions about consumers as research subjects. EMBO 

Rep. 2010 Aug;11(8):579-82. Epub 2010 Jul 16. No abstract available. 

75. Knoppers BM, Avard D, Howard HC. 2010. Direct-to-consumer genetic testing: driving choice? 

Expert Rev Mol Diagn. 2010 Nov;10(8):965-8. 

76. Fortier I, Burton PR, Robson PJ, Ferretti V, Little J, L'Heureux F, Deschênes M, Knoppers BM, 

Doiron D, et al. 2010. Quality, quantity and harmony: the DataSHaPER approach to integrating data 

across bioclinical studies. Int J Epidemiol. 2010 Oct;39(5):1383-93. 

77. Madadi P, Joly Y, Avard D, Chitayat DC, Smith MA, Ross CJ, Carleton BC, Hayden MR, Koren G. 

2010. Communicating pharmacogenetic research results to breastfeeding mothers taking codeine: a 

pilot study of perceptions and benefits. Clin Pharmacol Ther. 2010 Dec;88(6):792-5. Epub 2010 Aug 

25. 

78. Knoppers BM, Isasi R. 2010. Stem cell banking: between traceability and identifiability. Genome 

Med. 2010 Oct 5;2(10):73. 


79. Lévesque E, Leclerc D, Puymirat J, Knoppers BM. 2010. Developing registries of volunteers: key 

principles to manage issues regarding personal information protection. J Med Ethics. 2010 

Nov;36(11):712-4. Epub 2010 Sep 29. 

80. Ozdemir V, Knoppers BM. 2010. One size does not fit all: toward "upstream ethics"? Am J Bioeth 

10: 42-44. 

81. International Cancer Genome Consortium. (Knoppers BM as co-author). 2010. International 

network of cancer genome projects. Nature 464: 993-998. 

82. Knoppers BM. 2010. Consent to 'personal' genomics and privacy. Direct-to-consumer genetic tests 

and population genome research challenge traditional notions of privacy and consent. EMBO Rep 11: 

416-419. 

83. Borugian MJ, Robson P, Fortier I, Parker L, McLaughlin J, Knoppers BM, Bédard K, Gallagher RP, 

Sinclair S, Ferretti V, Whelan H, Hoskin D, Potter JD. 2010. The Canadian Partnership for Tomorrow 

Project: building a pan-Canadian research platform for disease prevention. CMAJ. 2010 Apr 26. 

84. Knoppers BM, Leroux T, Doucet H, Godard B, Laberge C, Stanton-Jean M, Fortin S, Cousineau J, 

Monardes C, Girard N, Levesque L, Durand C, Farmer Y, Dion-Labrie M, Bouthillier ME, Avard D. 

2010. Framing genomics, public health research and policy: points to consider. Public Health 

Genomics 13: 224-234. 

85. Bordet S, Nguyen TM, Knoppers BM, Isasi R. 2010. Use of umbilical cord blood for stem cell 

research. J Obstet Gynaecol Can 32: 58-61. 

86. Borry P, Howard HC, Sénécal K, Avard D. 2010. Health-related direct-to-consumer genetic testing: a 

review of companies' policies with regard to genetic testing in minors. Fam Cancer 9: 51-59. 

87. Bordet S, Bennett J, Knoppers BM, McNagny KM. 2010. The changing landscape of human-animal 

chimera research: A Canadian regulatory perspective. Stem Cell Res 4: 10-16. 

88. Bombard Y, Miller FA, Hayeems RZ, Avard D, Knoppers BM. 2010. Reconsidering reproductive 

benefit through newborn screening: a systematic review of guidelines on preconception, prenatal and 

newborn screening. Eur J Hum Genet. 2010 Jul;18(7):751-60. Epub 2010 Mar 3. 

89. Knoppers BM, Isasi R, Willemse L. 2010. Stem cell charter. Regen Med. 2010 Jan;5(1):5-6. 

90. Tassé AM, Budin-Ljøsne I, Knoppers BM, Harris JR. 2010. Retrospective access to data: the 

ENGAGE consent experience. Eur J Hum Genet 18: 741-745. 


2009 

MPS 

1. Feng J, Lupien A, Gingras H, Wasserscheid J, Dewar K, Legare D, Ouellette M. (2009) Genome 

sequencing of linezoid-resistant Streptococcus pneumoniae mutants reveals novel mechanisms of 

resistance. Genome Research 19: 1214-1223. 

Array 

2. Coulombe-Huntington J, Lam KC, Dias C, Majewski J. 2009. Fine-scale variation and genetic 

determinants of alternative splicing across individuals. PLoS Genet 5: e1000766. 

3. Ha KCh, Coulombe-Huntington J, Majewski J. 2009. Comparison of Affymetrix Gene Array with 

the Exon Array shows potential application for detection of transcript isoform variation. BMC 

Genomics 10: 519. 

4. Fiskerstrand T, Knappskog P, Majewski J, Wanders RJ, Boman H, Bindoff LA. (2009) A novel 

Refsum-life disorder that maps to chromosome 20. Neurology 72: 20-27. 

5. Ge B, Pokholok DK, Kwan T, Grundberg E, Morcos L, Verlaan DJ, Le J, Koka V, Lam KC, Gagné 

V, Dias J, Hoberman R, Montpetit A, Joly MM, Harvey EJ, Sinnett D, Beaulieu P, Hamon R, 

Graziani A, Dewar K, Harmsen E, Majewski J, Göring HH, Naumova AK, Blanchette M, Gunderson 

KL, Pastinen T. 2009. Global patterns of cis variation in human cells revealed by high-density allelic 

expression analysis. Nat Genet 41: 1216-1222. 

6. Verlaan DJ, Berlivet S, Hunninghake GM, Madore AM, Larivière M, Moussette S, Grundberg E, 

Kwan T, Ouimet M, Ge B, Hoberman R, Swiatek M, Dias J, Lam KC, Koka V, Harmsen E, Soto- 

Quiros M, Avila L, Celedón JC, Weiss ST, Dewar K, Sinnett D, Laprise C, Raby BA, Pastinen T, 

Naumova AK. 2009. Allele-specific chromatin remodeling in the ZPBP2/GSDMB/ORMDL3 locus 

associated with the risk of asthma and autoimmune disease. Am J Hum Genet 85: 377-393 

7. Verlaan D, Ge B, Grundberg E, Hoberman R, Lam KCL, Koka V, Dias J, Gurd S, Martin NW, 

Mallmin H, Nilsson O, Harmsen E, Dewar K, Kwan T, Pastinen T. (2009) Targeted screening of cisregulatory 

variation in human haplotypes. Genome Res 19: 118-127. 

8. Grundberg E, Kwan T, Ge B, Lam KC, Koka V, Kindmark A, Mallmin H, Dias J, Verlaan DJ, 

Ouimet M, Sinnett D, Rivadeneira F, Estrada K, Hofman A, van Meurs JM, Uitterlinden A, Beaulieu P, 

Graziani A, Harmsen E, Ljunggren O, Ohlsson C, Mellström D, Karlsson MK, Nilsson O, Pastinen T. 

2009. Population genomics in a disease targeted primary cell model. Genome Res 19: 1942-1952. 

9. Kwan T, Grundberg E, Koka V, Ge B, Lam KC, Dias C, Kindmark A, Mallmin H, Ljunggren O, 

Rivadeneira F, Estrada K, van Meurs JB, Uitterlinden A, Karlsson M, Ohlsson C, Mellström D, Nilsson 

O, Pastinen T, Majewski J. 2009. Tissue effect on genetic control of transcript isoform variation. 

PLoS Genet 5: e1000608. 

10. Hoberman R, Dias J, Ge B, Harmsen E, Mayhew M, Verlaan DJ, Kwan T, Dewar K, Blanchette M, 

Pastinen T. (2009) A probabilistic approach for SNP discovery in high-throughput human 

resequencing data. Genome Res. 2009 Jul 15. 

11. Qu HQ, Verlaan DJ, Ge B, Lu Y, Lam KC, Grabs R, Harmsen E, Hudson TJ, Hakonarson H, 

Pastinen T, Polychronakos C. 2009. A cis-acting regulatory variant in the IL2RA locus. J Immunol 

183: 5158-5162. 


12. Lerner-Ellis JP, Anastasio N, Liu J, Coelho D, Suormala T, Stucki M, Loewy AD, Gurd S, Grundberg 

E, Morel CF, Watkins D, Baumgartner MR, Pastinen T, Rosenblatt DS, Fowler B. (2009) Spectrum of 

mutations in MMACHC, allelic expression, and evidence for genotype-phenotype correlations. Hum 

Mutat 30: 1072-81. 

13. Wilson SG, Jones MR, Mullin BH, Dick IM, Richards JB, Pastinen TM, Grundberg E, Ljunggren 

O, Surdulescu GL, Dudbridge F, Elliott KS, Cervino ACL, Spector TD, Prince RL (2009) Common 

sequence variation in FLNB regulates bone structure in women in the general population and FLNB 

mRNA expression in osteoblasts in vitro. Journal of Bone and Mineral Research 24: 1989-1997. 

14. Richards JB, Waterworth D, O'Rahilly S, Hivert MF, Loos RJ, Perry JR, Tanaka T, Timpson NJ, 

Semple RK, et al. (R. Sladek and T.Pastinen are co-authors) 2009. A genome-wide association 

study reveals variants in ARL15 that influence adiponectin levels. PLoS Genet 5: e1000768. 

15. Loewy AD, Niles KM, Anastasio N, Watkins D, Lavoie J, Lerner-Ellis JP, Pastinen T, Trasler JM, 

Rosenblatt DS. (2009) Epigenetic modification of the gene for the vitamin B(12) chaperone MMACHC 

can result in increased tumorigenicity and methionine dependence. Mol Genet Metab. 96: 261-267. 

16. Falchi M, Bataille V, Hayward NK, Duffy DL, Bishop JA, Pastinen T, Cervino A, Zhao ZZ, Deloukas 

P, Soranzo N, Elder DE, Barrett JH, Martin NG, Bishop DT, Montgomery GW, Spector TD (2009) 

Genome-wide association study identifies variants at 9p21 and 22q13 associated with development 

of cutaneous nevi. Nat Genet 41: 915-919. 

17. Rivadeneira F, Styrkársdottir U, Estrada K, Halldórsson BV, Hsu YH, Richards JB, Zillikens MC, 

Kavvoura FK, Amin N, et al. (T. Pastinen is a co-author). 2009. Twenty bone-mineral-density loci 

identified by large-scale meta-analysis of genome-wide association studies. Nat Genet 41: 1199- 

1206. 

18. Bossé Y, Bacot F, Montpetit A, Rung J, Qu HQ, Engert JC, Polychronakos C, Hudson TJ, Froguel 

P, Sladek R, Desrosiers M. Identification of susceptibility genes for complex diseases using poolingbased 

genome-wide association scans. (2009) Human Genetics 125: 305-318. 

19. Anand SS, Xie C, Pare G, Montpetit A, Serre D, Rangarajan S, McQueen MJ, Cordell H, Keavney 

B, Yusuf S, Hudson TJ, Engert JC (2009) Genetic Variants Associated with Myocardial Infarction risk 

Factors in over 8,000 Individuals from Five Ethnic Groups: The INTERHEART Genetics Study. Circ 

Cardiovasc Genet 2: 16-25. 

20. Jacob K, Albrecht S, Sollier C, Faury D, Sader E, Montpetit A, Serre D, Hauser P, Garami M, 

Bognar L, Hanzely Z, Montes JL, Atkinson J, Farmer JP, Bouffet E, Hawkins C, Tabori U, Jabado N. 

(2009) Duplication of 7q34 is specific to juvenile pilocytic astrocytomas and a hallmark of cerebellar 

and optic pathway tumours. Br J Cancer. 

21. Bouron-Dal Soglio D, Rougemont AL, Absi R, Barrette S, Montpetit A, Fetni R, Fournet JC. (2009) 

SNP genotyping of a sclerosing rhabdomyosarcoma: reveals highly aneuploid profile and a specific 

MDM2/HMGA2 amplification. Hum Pathol 40: 1347-1352. 

22. Daley D, Lemire M, Akhabir L, Chan-Yeung M, He JQ, McDonald T, Sandford A, Stefanowicz D, 

Tripp B, Zamar D, Bosse Y, Ferretti V, Montpetit A, Tessier MC, Becker A, Kozyrskyj AL, Beilby J, 

McCaskie PA, Musk B, Warrington N, James A, Laprise C, Palmer LJ, Paré PD, Hudson TJ. (2009) 

Analyses of associations with asthma in four asthma population samples from Canada and Australia. 

Hum Genet 125: 445-459. 

23. Meyre D, Delplanque J, Chèvre JC, Lecoeur C, Lobbens S, Gallina S, Durand E, Vatin V, Degraeve 

F, Proença C, Gaget S, Körner A, Kovacs P, Kiess W, Tichet J, Marre M, Hartikainen AL, Horber F, 

Potoczna N, Hercberg S, Levy-Marchal C, Pattou F, Heude B, Tauber M, McCarthy MI, Blakemore 


AI, Montpetit A, Polychronakos C, Weill J, Coin LJ, Asher J, Elliott P, Järvelin MR, Visvikis-Siest S, 

Balkau B, Sladek R, Balding D, Walley A, Dina C, Froguel P (2009) Genome-wide association study 

for early-onset and morbid adult obesity identifies three new risk loci in European populations. Nat 

Genet 41: 157-159. 

24. Rung J, Cauchi S, Albrechtsen A, Shen L, Rocheleau G, Cavalcanti-Proença C, Bacot F, Balkau B, 

Belisle A, Borch-Johnsen K, Charpentier G, Dina C, Durand E, Elliott P, Hadjadj S, Järvelin MR, 

Laitinen J, Lauritzen T, Marre M, Mazur A, Meyre D, Montpetit A, Pisinger C, Posner B, Poulsen P, 

Pouta A, Prentki M, Ribel-Madsen R, Ruokonen A, Sandbaek A, Serre D, Tichet J, Vaxillaire M, 

Wojtaszewski JF, Vaag A, Hansen T, Polychronakos C, Pedersen O, Froguel P, Sladek R. 2009. 

Genetic variant near IRS1 is associated with type 2 diabetes, insulin resistance and hyperinsulinemia. 

Nat Genet 41: 1110-1115. 

25. Bouatia-Naji N, Bonnefond A, Cavalcanti-Proença C, Sparsø T, Holmkvist J, Marchand M, 

Delplanque J, Lobbens S, Rocheleau G, et al. (R. Sladek is a co-author). (2009) A variant near 

MTNR1B is associated with increased fasting plasma glucose levels and type 2 diabetes risk. Nat 

Genet 41: 89-94. 

26. Le Clerc S, Limou S, Coulonges C, Carpentier W, Dina C, Taing L, Delaneau O, Labib T, Sladek R; 

et al.. 2009. Genomewide association study of a rapid progression cohort identifies new susceptibility 

alleles for AIDS (ANRS Genomewide Association Study 03). J Infect Dis 200: 1194-201. 

27. Limou S, Le Clerc S, Coulonges C, Carpentier W, Dina C, Delaneau O, Labib T, Taing L, Sladek R; 

ANRS Genomic Group, Deveau C, Ratsimandresy R, Montes M, Spadoni JL, Lelièvre JD, Lévy Y, 

Therwath A, Schächter F, Matsuda F, Gut I, Froguel P, Delfraissy JF, Hercberg S, Zagury JF. (2009) 

Genomewide Association Study of an AIDS-Nonprogression Cohort Emphasizes the Role Played by 

HLA Genes (ANRS Genomewide Association Study 02). J Infect Dis 199: 419-426. 

28. Bonnefond A, Vaxillaire M, Labrune Y, Lecoeur C, Chèvre JC, Bouatia-Naji N, Cauchi S, Balkau B, 

Marre M, et al. (R. Sladek is a co-author). 2009. Genetic variant in HK1 is associated with a 

proanemic state and A1C but not other glycemic control-related traits. Diabetes 58: 2687-2697. 

29. Kong A, Steinthorsdottir V, Masson G, Thorleifsson G, Sulem P, Besenbacher S, Jonasdottir A, 

Sigurdsson A, Kristinsson KT, Jonasdottir A, Frigge ML, Gylfason A, Olason PI, Gudjonsson SA, 

Sverrisson S, Stacey SN, Sigurgeirsson B, Benediktsdottir KR, Sigurdsson H, Jonsson T, 

Benediktsson R, Olafsson JH, Johannsson OT, Hreidarsson AB, Sigurdsson G; DIAGRAM 

Consortium (R. Sladek and G. Rocheleau are co-authors), Ferguson-Smith AC, Gudbjartsson DF, 

Thorsteinsdottir U, Stefansson K. 2009. Parental origin of sequence variants associated with complex 

diseases. Nature 462: 868-874. 

30. Nicolson TJ, Bellomo EA, Wijesekara N, Loder MK, Baldwin JM, Gyulkhandanyan AV, Koshkin V, 

Tarasov AI, Carzaniga R, et al. (R. Sladek is a co-author). (2009) Insulin storage and glucose 

homeostasis in mice null for the granule zinc transporter ZnT8 and studies of the type 2 diabetesassociated 

variants. Diabetes. Jun 19. 

31. Camateros P, Kanagaratham C, Henri J, Sladek R, Hudson TJ, Radzioch D. (2009) Modulation of 

the Allergic Asthma Transcriptome Following Resiquimod Treatment. Physiol Genomics 38: 303-318. 

32. Fulton DL, Sundararajan S, Badis G, Hughes TR, Wasserman WW, Roach JC, Sladek R. (2009) 

TFCat: the curated catalog of mouse and human transcription factors. Genome Biol 10: R29. 

Validation 

33. Villani AC, Franchimont D. 2009. The contribution of genetic studies in shifting the 

immunopathogenesis paradigm of Crohn's disease. Expert Rev Clin Immunol 5: 361-364. 


34. Villani AC, Lemire M, Louis E, Silverberg MS, Collette C, Fortin G, Nimmo ER, Renaud Y, Brunet S, 

Libioulle C, Belaiche J, Bitton A, Gaudet D, Cohen A, Langelier D, Rioux JD, Arnott ID, Wild GE, 

Rutgeerts P, Satsangi J, Vermeire S, Hudson TJ, Franchimont D. 2009. Genetic variation in the 

familial Mediterranean fever gene (MEFV) and risk for Crohn's disease and ulcerative colitis. PLoS 

One 4: e7154. 

35. Villani AC, Lemire M, Fortin G, Louis E, Silverberg MS, Collette C, Baba N, Libioulle C, Belaiche J, 

Bitton A, Gaudet D, Cohen A, Langelier D, Fortin PR, Wither JE, Sarfati M, Rutgeerts P, Rioux JD, 

Vermeire S, Hudson TJ, Franchimont D. (2009) Common variants in the NLRP3 region contribute to 

Crohn's disease susceptibility. Nat Genet 41: 71-76. 

36. Fortin G, Yurchenko K, Collette C, Rubio M, Villani AC, Bitton A, Sarfati M, Franchimont D. 2009. L- 

carnitine, a diet component and organic cation transporter OCTN ligand, displays immunosuppressive 

properties and abrogates intestinal inflammation. Clin Exp Immunol 156: 161-171. 

37. Qu HQ, Bradfield JP, Bélisle A, Grant SF, Hakonarson H, Polychronakos C; Type I Diabetes 

Genetics Consortium. 2009. The type I diabetes association of the IL2RA locus. Genes Immun. 2009 

Dec;10 Suppl 1:S42-8. 

38. Warby SC, Montpetit A, Hayden AR, Carroll JB, Butland SL, Visscher H, Collins JA, Semaka A, 

Hudson TJ, Hayden MR. (2009) CAG expansion in the Huntington disease gene is associated with a 

specific and targetable predisposing haplogroup. Am J Hum Genet 84: 351-366. 

39. Manges AR, Tellis PA, Vincent C, Lifeso K, Geneau G, Reid-Smith RJ, Boerlin P. 2009. Multi-locus 

variable number tandem repeat analysis for Escherichia coli causing extraintestinal infections. J 

Microbiol Methods 79: 211-213. 

Proteomics 

40. Bell AW, Deutsch EW, Au CE, Kearney RE, Beavis R, Sechi S, Nilsson T, Bergeron JJ et al. 

(Houle B, Laboissiere S are co-authors). (2009)A HUPO test sample study reveals common 

problems in mass spectrometry-based proteomics. Nat Methods 6: 423-430. 

41. Bijian K, Mlynarek AM, Balys RL, Jie S, Xu Y, Hier MP, Black MJ, Di Falco MR, Laboissiere S, 

Alaoui-Jamali MA. (2009) Serum proteomic approach for the identification of serum biomarkers 

contributed by oral squamous cell carcinoma and host tissue microenvironment. J Proteome Res 8: 

2173-2185. 

42. Fang Q, Strand A, Law W, Faca VM, Fitzgibon MP, Hamel N, Houle B, Liu X, May DH, Poschmann 

G, Roy L, Stühler K, Ying W, Zhang J, Zheng Z, Bergeron JJ, Hanash S, He F, Leavitt BR, Meyer 

HE, Qian X, McIntosh MW. (2009) Brain-specific proteins decline in the cerebrospinal fluid of humans 

with Huntington's disease. Mol Cell Proteomics 8: 451-466. 

43. Sadvakassova G, Dobocan MC, DiFalco MR, Congote LF. (2009) Regulator of differentiation 1 

(ROD1) binds to the amphipathic C-terminal peptide of thrombospondin-4 and is involved in its 

mitogenic activity. J Cell Physiol 220: 672-679. 

44. Al Badaai Y, DiFalco MR, Tewfik MA, Samaha M. (2009) Quantitative proteomics of nasal mucus in 

chronic sinusitis with nasal polyposis. J Otolaryngol Head Neck Surg 38: 381-9. 

45. Ouellette S, Bell AW, van Oostrum J, Bergeron J. 2009. Report on the Barbados Workshop. Mol 

Cell Proteomics 8: 1450-1452. 

46. Nilsson T, Au CE, Bergeron JJ. 2009. Sorting out glycosylation enzymes in the Golgi apparatus. 

FEBS Lett 583: 3764-3769. 


47. Cameron PH, Chevet E, Pluquet O, Thomas DY, Bergeron JJ. 2009. Calnexin phosphorylation 

attenuates the release of partially misfolded alpha1-antitrypsin to the secretory pathway. J Biol Chem 

284: 34570-34579. 

48. Archakov A, Bergeron JJ, Khlunov A, Lisitsa A, Paik YK. 2009. The Moscow HUPO Human 

Proteome Project workshop. Mol Cell Proteomics 8: 2199-2200. 

Bio-informatics 

49. Murie C, Woody O, Lee AY, Nadon R. (2009) Comparison of small n statistical tests of differential 

expression applied to microarrays. BMC Bioinformatics 10:45. 

50. Diallo AB, Badescu D, Blanchette M, Makarenkov V. 2009. A whole genome study and identification 

of specific carcinogenic regions of the human papilloma viruses. J Comput Biol 16: 1461-1473. 

51. Bertrand D, Blanchette M, El-Mabrouk N. 2009. Genetic map refinement using a comparative 

genomic approach. J Comput Biol 16: 1475-1486. 

52. Mongin E, Dewar K, Blanchette M. 2009. Long-range regulation is a major driving force in 

maintaining genome integrity. BMC Evol Biol 9: 203. 

53. Cloutier P, Al-Khoury R, Lavallée-Adam M, Faubert D, Jiang H, Poitras C, Bouchard A, Forget D, 

Blanchette M, Coulombe B. (2009) High-resolution mapping of the protein interaction network for the 

human transcription machinery and affinity purification of RNA polymerase II-associated complexes. 

Methods 48: 381-386. 

54. Fraser J, Rousseau M, Shenker S, Ferraiuolo MA, Hayashizaki Y, Blanchette M, Dostie J. (2009) 

Chromatin conformation signatures of cellular differentiation. Genome Biol 10: R37. 

Functional Genomics 

55. Shutong Tse, Laura Bradbury, Justin W.L. Wana, Haig Djambazian, Robert Sladek, Thomas 

Hudson (2009) A combined watershed and level set method for segmentation of brightfield cell 

images. Medical Imaging 7259: 72593G-72593G. 

56. Perrault CM, Qasaimeh MA, Juncker D. (2009) The microfluidic probe: operation and use for 

localized surface processing. J Vis Exp 4: 1418. 

Ethics 

57. Toronto International Data Release Workshop Authors, (Dewar K and Knoppers BM are coauthors). 

2009. Prepublication data sharing. Nature 461: 168-170. 

58. Knoppers BM, Abdul-Rahman MH. 2009. Health privacy in genetic research. Politics Life Sci 28: 99- 

101. 

59. Knoppers BM, Laberge C. 2009. Return of "accurate" and "actionable" results: yes! Am J Bioeth 9: 

107-109. 

60. Khoury MJ, Bertram L, Boffetta P, Butterworth AS, Chanock SJ, Dolan SM, Fortier I, Garcia-Closas 

M, Gwinn M, Higging JPT, Cecile A, Janssens JW, Ostell J, Owen RP, Pagon RA, Rebbeck TR, 

Rothman N, Bernstein JL, Burton PR, Campbell H, Chockalingam A, Furberg H, Little J, O'Brien TR, 

Seminara D, Vineis P, Winn DM, Yu W, Ioannidis JPA. (2009) Genome-wide association studies, field 

synopses, and the development of the knowledge Base on genetic variation and human diseases. 

Am. J. Epidemiol. 


61. Little J, Higgins J, Ioannidis J, Moher D, Gagnon F, Von Elm E, Khoury M, Cohen B, Davey-Smith G, 

Grimshaw J, et al. ( Fortier I is a co-author). (2009) Strengthening the reporting of genetic 

association studies (STREGA)- an extension of the strenghtening of the reporting of observational 

studies in epidemiology (STROBE) statement. Journal of Clinical Epidemiology 62: 597-608. 

62. Bombard Y, Miller FA, Hayeems RZ, Avard D, Knoppers BM, Cornel MC, Borry P. 2009. The 

expansion of newborn screening: is reproductive benefit an appropriate pursuit? Nat Rev Genet 10: 

666-667. 

63. Gurwitz D, Fortier I, Lunshof JE, Knoppers BM. 2009. Research ethics. Children and population 

biobanks. Science 325: 818-819. 

64. Knoppers BM, Bordet S, Isasi R (2009) The human embryo: ethical and legal aspects. Methods Mol 

Biol 550: 281-305. 


2008 

Array 

1. Houlston RS, Webb E, Broderick P, Pittman AM, Di Bernardo MC, Lubbe S, Chandler I, 

Vijayakrishnan J, Sullivan K, et al. (A Montpetit and T.J. Hudson are co-authors) (2008) Metaanalysis 

of genome-wide association data identifies four new susceptibility loci for colorectal cancer. 

Nat Genet 40: 1426-1435. 

2. McKay JD, Hung RJ, Gaborieau V, Boffetta P, Chabrier A, Byrnes G, Zaridze D, Mukeria A, 

Szeszenia-Dabrowska N, et al., (A Montpetit is a co-author) (2008) Lung cancer susceptibility locus 

at 5p15.33. Nat Genet 40: 1404-1406. 

3. Keating BJ, Tischfield S, Murray SS, Bhangale T, Price TS, Glessner JT, Galver L, Barrett JC, Grant 

SF, Farlow DN, et al., (A Montpetit is a co-author) (2008) Concept, design and implementation of a 

cardiovascular gene-centric 50 k SNP array for large-scale genomic association studies. PLoS ONE 

3: e3583. 

4. Chao MJ, Barnardo MC, Lincoln MR, Ramagopalan SV, Herrera BM, Dyment DA, Montpetit A, 

Sadovnick AD, Knight JC, Ebers GC (2008) HLA class I alleles tag HLA-DRB1*1501 haplotypes for 

differential risk in multiple sclerosis susceptibility. Proc Natl Acad Sci U S A. 105: 13069-13074. 

5. Tenesa A, Farrington SM, Prendergast JG, Porteous ME, Walker M, Haq N, Barnetson RA, 

Theodoratou E, Cetnarskyj R, et al. (A Montpetit and T.J. Hudson are co-authors) (2008) Genomewide 

association scan identifies a colorectal cancer susceptibility locus on 11q23 and replicates risk 

loci at 8q24 and 18q21. Nat Genet 40: 631-637. 

6. Zogopoulos G, Jorgensen C, Bacani J, Montpetit A, Lepage P, Ferretti V, Chad L, Selvarajah S, 

Zanke B, Hudson TJ, Pawson T, Gallinger S (2008) Germline EPHB2 receptor variants in familial 

colorectal cancer. PLoS ONE 3: e2885. 

7. Bouron-Dal Soglio D, Rougemont AL, De Buys Roessingh AS, Fetni R, Rypens F, Bouchard S, 

Montpetit A, Fournet JC (2008) Chondroid cystic malformation of the lung with trisomy 8 mosaicism: 

a new cystic lung malformation. Am J Surg Pathol 32: 1095-1100. 

8. Tremblay K, Daley D, Chamberland A, Lemire M, Montpetit A, Laviolette M, Musk AW, James AL, 

Chan-Yeung M, Becker A, Kozyrskyj AL, Sandford AJ, Hudson TJ, Paré PD, Laprise C (2008) 

Genetic variation in immune signaling genes differentially expressed in asthmatic lung tissues. J 

Allergy Clin Immunol 122: 529-536. 

9. Bemmo A, Benovoy D, Kwan T, Gaffney DJ, Jensen RV, Majewski J. (2008) Gene expression and 

isoform variation analysis using Affymetrix Exon arrays. BMC Genomics, 9: 529-544. 

10. Benovoy D, Kwan T, Majewski J (2008) Effect of polymorphisms within probe-target sequences on 

olignonucleotide microarray experiments. Nucleic Acids Res.36: 4417-4423. 

11. Sigurdsson S, Nordmark G, Garnier S, Grundberg E, Kwan T, Nilsson O, Eloranta ML, Gunnarsson 

I, Svenungsson E, Sturfelt G, Bengtsson AA, Jönsen A, Truedsson L, Rantapää-Dahlqvist S, 

Eriksson C, Alm G, Göring HH, Pastinen T, Syvänen AC, Rönnblom L (2008) A risk haplotype of 

STAT4 for systemic lupus erythematosus is over-expressed, correlates with anti-dsDNA and shows 

additive effects with two risk alleles of IRF5. Hum Mol Genet. 17: 2868-2876. 

12. Richards JB, Rivadeneira F, Inouye M, Pastinen TM, Soranzo N, Wilson SG, Andrew T, Falchi M, 

Gwilliam R, Ahmadi KR, Valdes AM, Arp P, Whittaker P, Verlaan DJ, Jhamai M, Kumanduri V, 

Moorhouse M, van Meurs JB, Hofman A, Pols HA, Hart D, Zhai G, Kato BS, Mullin BH, Zhang F, 


Deloukas P, Uitterlinden AG, Spector TD (2008) Bone mineral density, osteoporosis, and 

osteoporotic fractures: a genome-wide association study. Lancet 371: 1505-1512. 

13. Kwan T, Benovoy D, Dias C, Gurd S, Provencher C, Beaulieu P, Hudson TJ, Sladek R, Majewski 

J (2008) Genome-wide analysis of transcript isoform variation in humans. Nat. Genet 40: 225-31. 

14. Pollard KS, Serre D, Wang X, Tao H, Grundberg E, Hudson TJ, Clark AG, Frazer K (2008) A 

genome-wide approach to identifying novel-imprinted genes. Hum Genet 122: 625-634. 

15. Serre D, Montpetit A, Paré G, Engert JC, Yusuf S, Keavney B, Hudson TJ, Anand S (2008) 

Correction of Population Stratification in Large Multi-Ethnic Association Studies. PLoS ONE 3: e1382. 

16. Serre D, Gurd S, Ge B, Sladek R, Sinnett D, Harmsen E, Bibikova M, Chudin E, Barker DL, 

Dickinson T, Fan JB, Hudson TJ (2008) Differential Allelic Expression in the Human Genome: A 

Robust Approach To Identify Genetic and Epigenetic Cis-Acting Mechanisms Regulating Gene 

Expression. PLoS Genet 4: e1000006. 

17. Grundberg E, Brandstrom H, Lam KC, Gurd S, Ge B, Harmsen E, Kindmark A, Ljunggren O, 

Mallmin H, Nilsson O, Pastinen TM (2008) Systematic Assessment of the Human Osteoblast 

Transcriptome in Resting and Induced Primary Cells. Physiol Genomics 33: 301-11. 

18. Bouatia-Naji N, Rocheleau G, Van Lommel L, Lemaire K, Schuit F, Cavalcanti-Proenca C, Marchand 

M, Hartikainen A, Sovio U, De Graeve F, Rung J, Vaxillaire M, Tichet J, Marre M, Balkau B, Weill J, 

Elliott P, Jarvelin MR, Meyre D, Polychronakos C, Dina C, Sladek R, Froguel P. (2008) A 

polymorphism within the G6PC2 gene is associated with fasting plasma glucose levels. Science 

(320):1085-1088. 

19. Cauchi S, Meyre D, Durand E, Proença C, Marre M, Hadjadj S, Choquet H, De Graeve F, Gaget S, 

Allegaert F, Delplanque J, Permutt MA, Wasson J, Blech I, Charpentier G, Balkau B, Vergnaud AC, 

Czernichow S, Patsch W, Chikri M, Glaser B, Sladek R, Froguel P (2008) Post genome-wide 

association studies of novel genes associated with type 2 diabetes show gene-gene interaction and 

high predictive value. PLoS ONE 3: e2031. 

20. de Smith AJ, Walters RG, Coin LJ, Steinfeld I, Yakhini Z, Sladek R, Froguel P, Blakemore AI (2008) 

Small deletion variants have stable breakpoints commonly associated with alu elements. PLoS ONE 

3: e3104. 

21. Gregory DJ, Sladek R, Olivier M, Matlashewski G (2008) Comparison of the Effects of Leishmania 

major or Leishmania donovani Infection on Macrophage Gene Expression. Infect Immun 76: 1186- 

1192. 

22. Berry FB, Skarie JM, Mirzayans F, Fortin Y, Hudson TJ, Raymond V, Link BA, Walter MA (2008) 

FOXC1 is required for cell viability and resistance to oxidative stress in the eye through the 

transcriptional regulation of FOXO1A. Hum Mol Genet 17: 490-505. 

23. Tremblay K, Lemire M, Potvin C, Tremblay A, Hunninghake GM, Raby BA, Hudson TJ, Perez- 

Iratxeta C, Andrade-Navarro MA, Laprise C (2008) Genes to diseases (G2D) computational method 

to identify asthma candidate genes. PLoS ONE 6: e2907. 

Proteomics 

24. Asp L, Kartberg F, Fernandez-Rodriguez J, Smedh M, Elsner M, Laporte F, Bárcena M, Jansen KA, 

Valentijn JA, Koster AJ, Bergeron JJ, Nilsson T. (2008) Early Stages of Golgi-Vesicle and -Tubule 

Formation Require Diacylglycerol. Mol Biol Cell. 


25. Yanofsky CM, Kearney RE, Lesimple S, Bergeron JJ, Boismenu D, Carrillo B, Bell AW. (2008) A 

Bayesian approach to peptide identification using Accurate Mass and Time tags from LC-FTICR-MS 

proteomics experiments. Conf Proc IEEE Eng Med Biol Soc. 1: 3775-3778. 

26. Segura MM, Garnier A, Di Falco MR, Whissell G, Meneses-Acosta A, Arcand N, Kamen A (2008) 

Identification of Host Proteins Associated with Retroviral Vector Particles by Proteomic Analysis of 

Highly Purified Vector Preparations. J Virology 82: 1107-1117. 


27. Murie C, Nadon R. (2008) A correction for estimating error when using the Local Pooled Error 

Statistical Test. Bioinformatics. 24: 1735-1736. 

28. Khoury I, Toussaint G, Ciampi A., Antoniano I, Murie C, Nadon R. (2008). Proximity-Graph-Based 

Tools for DNA Clustering. In John Wang (Editor) Encyclopedia of Data Warehousing and Mining (2nd 

edition). Hershey, PA: IGI Global Books. 

29. Mills JR, Hippo Y, Robert F, Chen SM, Malina A, Lin CJ, Trojahn U, Wendel HG, Charest A, Bronson 

RT, Kogan SC, Nadon R, Housman DE, Lowe SW, Pelletier J (2008) TORC1 promotes survival 

through translational control of Mcl-1. Proc Natl Acad Sci U S A. 105: 10853-10858. 

30. Gaffney DJ, Blekhman R, Majewski J (2008) Selective constraints in experimentally defined primate 

regulatory regions. PLoS Genet 4: e1000157. 

31. Gaffney DJ, Keightley PD. (2008) Effect of the assignment of ancestral CpG state on the estimation 

of nucleotide substitution rates in mammals. BMC Evol Biol 8:265. 

32. Fauteux F, Blanchette M, Strömvik MV (2008) Seeder: Discriminative Seeding DNA Motif Discovery. 

Bioinformatics Aug 21. 

33. Blanchette M, Diallo AB, Green ED, Miller W, Haussler D (2008) Computational reconstruction of 

ancestral DNA sequences. Methods Mol Biol. 422: 171-184. 

34. Coulombe B, Blanchette M, Jeronimo C. Steps towards a repertoire of comprehensive maps of 

human protein interaction networks: the Human Proteotheque Initiative (HuPI) (2008) Biochem Cell 

Biol. 86: 149-156. 

35. Smith M, Blanchette M, Papadopoulou B (2008) Improving the prediction of mRNA extremities in the 

parasitic protozoan Leishmania.BMC Bioinformatics 9: 158. 

Validation 

36. Montpetit A, Côté S, Brustein E, Drouin CA, Lapointe L, Boudreau M, Meloche C, Drouin R, 

Hudson TJ, Drapeau P, Cossette P. (2008) Disruption of AP1S1, causing a novel neurocutaneous 

syndrome, perturbs development of the skin and spinal cord. PLoS Genet 4:e1000296. 

37. Do R, Bailey SD, Desbiens K, Belisle A, Montpetit A, Bouchard C, Pérusse L, Vohl MC, Engert JC 

(2008) Genetic variants of FTO influence adiposity, insulin sensitivity, leptin levels, and resting 

metabolic rate in the Quebec Family Study. Diabetes 57: 1147-1150. 

38. Satou Y, Mineta K, Ogasawara M, Sasakura Y, Shoguchi E, Ueno K, Yamada L, Matsumoto J, 

Wasserscheid J, Dewar K, Wiley GB, Macmil SL, Roe BA, Zeller RW, Hastings KE, Lemaire P, 

Lindquist E, Endo T, Hotta K, Inaba K. Improved genome assembly and evidence-based global gene 

model set for the chordate Ciona intestinalis: new insight into intron and operon populations. (2008) 

Genome Biol 9: R152. 


39. Do R, Paré G, Montpetit A, Hudson TJ, Gaudet D, Engert JC (2008) K45R variant of squalene 

synthase increases total cholesterol levels in two study samples from a French Canadian population. 

Hum Mutat 29: 689-694. 

40. Engert JC, Lemire M, Faith J, Brisson D, Fujiwara TM, Roslin NM, Brewer CG, Montpetit A, 

Darmond-Zwaig C, Renaud Y, Doré C, Bailey SD, Verner A, Tremblay G, St-Pierre J, Bétard C, 

Platko J, Rioux JD, Morgan K, Hudson TJ, Gaudet D (2008) Identification of a chromosome 8p locus 

for early-onset coronary heart disease in a French Canadien population. Eur J Hum Genet 16: 105- 

114. 

41. Graham DS, Vyse TJ, Fortin PR, Montpetit A, Cai YC, Lim S, McKenzie T, Farwell L, Rhodes B, 

Chad L, Hudson TJ, Sharpe A, Terhorst C, Greenwood CM, Wither J, Rioux JD; CaNIOS GenES 

Investigators (2008) Association of LY9 in UK and Canadian SLE families. Genes Immun 9: 93-102. 

42. Plante M, Claveau S, Lepage P, Lavoie EM, Brunet S, Roquis D, Morin C, Vézina H, Laprise C 

(2008) Mucolipidosis II: a single causal mutation in the N-acetylglucosamine-1-phosphotransferase 

gene (GNPTAB) in a French Canadian founder population. Clin Gen 73: 236-244. 

43. Madore AM, Tremblay K, Hudson TJ, Laprise C (2008) Replication of an association between 17q21 

SNPs and asthma in a French-Canadian familial collection. Hum Genet 123: 93-95. 

44. Tewfik MA, Bossé Y, Hudson TJ, Vallée-Smejda S, Al-Shemari H, Desrosiers M. (2008) 

Assessment of Toll-like receptor 2 gene polymorphisms in severe chronic rhinosinusitis. J Otolaryngol 

Head Neck Surg 37: 552-558. 

45. Amemiya CT, Prohaska SJ, Hill-Force A, Cook A, Wasserscheid J, Ferrier DE, Pascual-Anaya J, 

Garcia-Fernàndez J, Dewar K, Stadler PF (2008) The Amphioxus Hox Cluster: Characterization, 

Comparative Genomics and Evolution. J Exp Zoolog B Mol Dev Evol 310: 1-13. 

46. Zhang Z, Quinlan J, Hoy W, Hughson MD, Lemire M, Hudson TJ, Hueber PA, Benjamin A, Roy A 

Pascuet E, Goodyer M, Raju C, Houghton F, Bertram J, Goodyer P. (2008) A common RET variant 

is associated with reduced newborn kidney size and function. J. Am. Soc. Nephrol. 19: 2027-2034. 

47. Al-Shemari H, Bossé Y, Hudson TJ, Cabaluna M, Duval M, Lemire M, Vallee-Smedja S, Frenkiel S, 

Desrosiers M (2008) Influence of leukotriene gene polymorphisms on chronic rhinosinusitis.BMC Med 

Genet 9: 21. 

48. Yang L, Andrade MF, Labialle S, Moussette S, Geneau G, Sinnett D, Belisle A, Greenwood CMT 

and Naumova AK (2008) Parental Effect of DNA (Cytosine-5) Methyltransferase 1 on Grandparental- 

Origin-Dependent. Genetics 178: 35-45. 


2007 

Array 

1. Sabeti PC, Varilly P, Fry B, Lohmueller J, Hostetter E, Cotsapas C, Xie X, Byrne EH, McCarroll SA, 

Gaudet R, Schaffner SF, Lander ES; International HapMap Consortium (Montpetit A, Chagnon F, 

Ferretti V, Leboeuf M, Olivier JF, Phillips M, Roumy S, Verner A, Hudson TJ are on the author 

list as members of the McGill University and Genome Quebec Innovation Centre team) (2007) 

Genome-wide detection and characterization of positive selection in human populations. Nature 449: 

913-918. 

2. Kwan T, Benovoy D, Dias C, Gurd S, Serre D, Zuzan H, Clark TA, Schweitzer A, Staples MK, 

Wang H, Blume JE, Hudson TJ, Sladek R, Majewski J. (2007) Heritability of alternative splicing in 

the human genome. Genome Res 17: 1210-1218. The platform ran the Exon arrays and helped for 

the analysis 

3. International HapMap Consortium (Montpetit A, Chagnon F, Ferretti V, Leboeuf M, Olivier JF, 

Phillips MS, Roumy S, Sallée C, Verner A, Hudson TJ are co-authors). (2007) A second 

generation human haplotype map of over 3.1 million SNPs. Nature 449: 851-61. 

4. Zanke BW, Greenwood CM, Rangrej J, Kustra R, Tenesa A, Farrington SM, Prendergast J, 

Olschwang S, Chiang T, Crowdy E, Ferretti V, Laflamme P, Sundararajan S, Roumy S, Olivier JF, 

Robidoux F, Sladek R, Montpetit A, Campbell P, Bezieau S, O'Shea AM, Zogopoulos G, Cotterchio 

M, Newcomb P, McLaughlin J, Younghusband B, Green R, Green J, Porteous ME, Campbell H, 

Blanche H, Sahbatou M, Tubacher E, Bonaiti-Pellié C, Buecher B, Riboli E, Kury S, Chanock SJ, 

Potter J, Thomas G, Gallinger S, Hudson TJ, Dunlop MG. (2007) Genome-wide association scan 

identifies a colorectal cancer susceptibility locus on chromosome 8q24. Nat Genet 39: 989-994. 

5. Zogopoulos G, Ha KC, Naqib F, Moore S, Kim H, Montpetit A, Robidoux F, Laflamme P, Cotterchio 

M, Greenwood C, Scherer SW, Zanke B, Hudson TJ, Bader GD, Gallinger S (2007) Germ-line DNA 

copy number variation frequencies in a large North American population. Hum Genet 122: 345-353. 

6. Reedik Magi , Arne Pfeufer , Mari Nelis, Alexandre Montpetit, Andres Metspalu and Maido Remm. 

Evaluating the performance of commercial whole-genome marker sets for capturing common genetic 

variation. BMC Genomics 2007, 8:159. Genotyping for the Estonian population used in the analysis 

was performed at Centre 

7. DeLuca GC, Ramagopalan SV, Herrera BM, Dyment DA, Lincoln MR, Montpetit A, Pugliatti M, 

Barnardo MC, Risch NJ, Sadovnick AD, Chao M, Sotgiu S, Hudson TJ, Ebers GC. (2007). An 

extreme of outcome strategy provides evidence that multiple sclerosis severity is determined by 

alleles at the HLA-DRB1 locus. Proc Natl Acad Sci USA 104: 20896-20901. 

8. Grundberg E, Lau EM, Pastinen T, Kindmark A, Nilsson O, Ljunggren O, Mellstrom D, Orwoll E, 

Redlund-Johnell I, Holmberg A, Gurd S, Leung PC, Kwok T, Ohlsson C, Mallmin H, Brandstrom H. 

Vitamin D Receptor 3' Haplotypes Are Unequally Expressed in Primary Human Bone Cells and 

Associated With Increased Fracture Risk: The MrOS Study in Sweden and Hong Kong. J Bone Miner 

Res. 2007 Jun;22 (6): 832-40 RNA expression analyses was performed by the platform 

9. Sladek R, Rocheleau G, Rung J, Dina C, Shen L, Serre D, Boutin P, Vincent D, Belisle A, Hadjadj 

S, Balkau B, Heude B, Charpentier G, Hudson TJ, Montpetit A, Pshezhetsky AV, Prentki M, Posner 

BI, Balding DJ, Meyre D, Polychronakos C, Froguel P. A genome-wide association study identifies 

novel risk loci for type 2 diabetes. Nature 2007 Feb 22;445 (7130): 881-5. Genotyping and some 

analyses were performed by the platform 


10. Cardin S, Libby E, Pelletier P, Le Bouter S, Shiroshita-Takeshita A, Le Meur N, Leger J, Demolombe 

S, Ponton A, Glass L, Nattel S. Contrasting gene expression profiles in two canine models of atrial 

fibrillation. Circ Res. 2007 Feb 16;100 (3): 425-33. Expression arrays were performed by the platform 

11. Kuroda KO, Meaney MJ, Uetani N, Fortin Y, Ponton A, Kato T (2007) ERK-FosB signaling in dorsal 

MPOA neurons plays a major role in the initiation of parental behavior in mice. Mol Cell Neurosci 36: 

121-131. 

12. Bifsha P, Landry K, Ashmarina L, Durand S, Seyrantepe V, Trudel S, Quiniou C, Chemtob S, Xu Y, 

Gravel RA, Sladek R, Pshezhetsky AV. Altered gene expression in cells from patients with lysosomal 

storage disorders suggests impairment of the ubiquitin pathway. Cell Death Differ. 2007 Mar;14 (3): 

511-23. Expression arrays were performed by the platform 

13. Brisson D, St-Pierre J, Santure M, Hudson TJ, Despres JP, Vohl MC, Gaudet D. Genetic epistasis in 

the VLDL catabolic pathway is associated with deleterious variations on triglyceridemia in obese 

subjects. Int J Obes (Lond) 2007 Mar 6. Genotyping was performed by the platform 

14. Qu HQ, Lu Y, Marchand L, Bacot F, Frechette R, Tessier MC, Montpetit A, Polychronakos C. 

Genetic control of alternative splicing in the TAP2 gene: possible implication in the genetics of type 1 

diabetes. Diabetes 2007 Jan;56 (1): 270-5. Genotyping was performed by the platform 

15. Benoit MH, Hudson TJ, Maire G, Squire JA, Arcand SL, Provencher D, Mes-Masson AM, Tonin PN. 

Global analysis of chromosome X gene expression in primary cultures of normal ovarian surface 

epithelial cells and epithelial ovarian cancer cell lines. Int J Oncol. 2007 Jan;30 (1): 5-17. Expression 

arrays were performed by the platform 

16. Bosse Y, Maghni K, Hudson TJ. 1alpha,25-dihydroxy-vitamin D3 stimulation of bronchial smooth 

muscle cells induces autocrine, contractility, and remodeling processes. Physiol Genomics 2007 Apr 

24; 29(2): 161-8. Expression arrays were performed by the platform 

17. Bosse Y, Hudson TJ. Toward a comprehensive set of asthma susceptibility genes. Annu Rev Med. 

2007 58:171-84. Review 

Validation 

18. Tewfik MA, Bosse Y, Hudson TJ, Desrosiers M (2007) Population-Based Association Study Of TLR 

Gene Polymorphisms In Chronic Rhinosinusitis. J Allergy Clin Immunol 119: S141-S149. 

19. Jasinska AJ, Service S, Levinson M, Slaten E, Lee O, Sobel E, Fairbanks LA, Bailey JN, Jorgensen 

MJ, Breidenthal SE, Dewar K, Hudson TJ, Palmour R, Freimer NB, Ophoff RA (2007) A genetic 

linkage map of the vervet monkey (Chlorocebus aethiops sabaeus). Mamm Genome. 18: 347-360 

BAC sequencing was performed by the platform 

20. Quinlan J, Lemire M, Hudson T, Qu H, Benjamin A, Roy A, Pascuet E, Goodyer M, Raju C, Zhang Z, 

Houghton F, Goodyer P. A Common Variant of the PAX2 Gene Is Associated with Reduced Newborn 

Kidney Size. J Am Soc Nephrol. 2007 Jun;18 (6): 1915-21. Genotyping and some association 

analysis were performed at the Centre. 

21. Labuda D, Labbe C, Langlois S, Lefebvre JF, Freytag V, Moreau C, Sawicki J, Beaulieu P, Pastinen 

T, Hudson TJ, Sinnett D. Patterns of variation in DNA segments upstream of transcription start sites. 

Hum Mutat. 2007 May;28 (5): 441-50. Sequencing and some analysis was performed by the platform. 

22. Begin P, Tremblay K, Daley D, Lemire M, Claveau S, Salesse C, Kacel S, Montpetit A, Becker A, 

Chan-Yeung M, Kozyrskyj AL, Hudson TJ, Laprise C. Association of urokinase-type plasminogen 

activator with asthma and atopy. Am J Respir Crit Care Med. 2007 Jun 1;175 (11): 1109-16. 


23. Gutierrez-Aguilar R, Benmezroua Y, Balkau B, Marre M, Helbecque N, Charpentier G, Polychronakos 

C, Sladek R, Froguel P, Neve B (2007) Minor contribution of SMAD7 and KLF10 variants to genetic 

susceptibility of type 2 diabetes. Diabetes Metab 33: 372-378. 

24. Gutiérrez-Aguilar R, Benmezroua Y, Vaillant E, Balkau B, Marre M, Charpentier G, Sladek R, Froguel 

P, Neve B (2007) Analysis of KLF transcription factor family gene variants in type 2 diabetes. BMC 

Med Genet 8:53. 

25. Qu HQ, Montpetit A, Ge B, Hudson TJ, Polychronakos C. Toward further mapping of the 

association between the IL2RA locus and type 1 diabetes. Diabetes 2007 Apr;56 (4): 1174-6. 

Genotyping and assay design were performed by the platform. 

26. Pare G, Serre D, Brisson D, Anand SS, Montpetit A, Tremblay G, Engert JC, Hudson TJ, Gaudet D. 

Genetic analysis of 103 candidate genes for coronary artery disease and associated phenotypes in a 

founder population reveals a new association between endothelin-1 and high-density lipoprotein 

cholesterol. Am J Hum Genet. 2007 Apr;80 (4): 673-82. Genotyping, assay design and some 

analyses were performed by the platform. 

27. Tischkowitz M, Xia B, Sabbaghian N, Reis-Filho JS, Hamel N, Li G, van Beers EH, Li L, Khalil T, 

Quenneville LA, Omeroglu A, Poll A, Lepage P, Wong N, Nederlof PM, Ashworth A, Tonin PN, Narod 

SA, Livingston DM, Foulkes WD. Analysis of PALB2/FANCN-associated breast cancer families. Proc 

Natl Acad Sci U S A 2007 Apr 17;104 (16): 6788-93. Sequencing was performed by the platform. 

28. Hersh CP, Soto-Quiros ME, Avila L, Lake SL, Liang C, Fournier E, Spesny M, Sylvia JS, Lazarus R, 

Hudson T, Verner A, Klanderman BJ, Freimer NB, Silverman EK, Celedon JC. Genome-wide 

linkage analysis of pulmonary function in families of children with asthma in Costa Rica. Thorax 2007 

Mar;62 (3): 224-30. Genotyping was performed by the platform. 

29. Raby BA, Soto-Quiros ME, Avila L, Lake SL, Murphy A, Liang C, Fournier E, Spesny M, Sylvia JS, 

Verner A, Hudson TJ, Klanderman BJ, Freimer NB, Silverman EK, Celedon JC. Sex-specific linkage 

to total serum immunoglobulin E in families of children with asthma in Costa Rica. Hum Mol Genet. 

2007 Feb 1;16 (3): 243-53. Genotyping was performed by the platform. 

30. Freimer NB, Service SK, Ophoff RA, Jasinska AJ, McKee K, Villeneuve A, Belisle A, Bailey JN, 

Breidenthal SE, Jorgensen MJ, Mann JJ, Cantor RM, Dewar K, Fairbanks LA (2007) A quantitative 

trait locus for variation in dopamine metabolism mapped in a primate model using reference 

sequences from related species. Proc Natl Acad Sci U S A 104: 15811-15816. 

31. Celedon JC, Soto-Quiros ME, Avila L, Lake SL, Liang C, Fournier E, Spesny M, Hersh CP, Sylvia JS, 

Hudson TJ, Verner A, Klanderman BJ, Freimer NB, Silverman EK, Weiss ST. Significant linkage to 

airway responsiveness on chromosome 12q24 in families of children with asthma in Costa Rica. Hum 

Genet. 2007 Jan;120 (5): 691-9. Genotyping was performed by the platform. 

Proteomics 

32. Yanofsky CM, Kearney RE, Lesimple S, Bergeron JJ, Boismenu D, Carrillo B, Bell AW (2007) 

Quantification of uncertainty of peptide retention time predictions from a sequence-based model in 

LC-MS/MS proteomics experiments. Conf Proc IEEE Eng Med Biol Soc 2007:1221-1224. 

33. Jutras I, Houde M, Currier N, Boulais J, Duclos S, LaBoissière S, Bonneil E, Kearney P, Thibault P, 

Paramithiotis E, Hugo P, Desjardins M (2007) Modulation of the phagosome proteome by inteferon-γ. 

Mol Cell Proteomics 7: 697-715. 

34. Tewfik MA, Latterich M, DiFalco MR, Samaha M (2007) Proteomics of nasal mucus in chronic 

rhinosinusitis. Am J Rhinol 21: 680-685. 


35. Caruso ME, Jenna S, Bouchecareilh M, Baillie DL, Boismenu D, Halawani D, Latterich M, Chevet E 

(2008) GTPase-mediated regulation of the unfolded protein response in Caenorhabditis elegans is 

dependent on the AAA+ ATPase CDC-48. Mol. Cell Biol. 28: 4261-4274. 

36. Emadali A, Metrakos PP, Kalantari F, Boutros T, Boismenu D, Chevet E. Proteomic analysis of 

tyrosine phosphorylation during human liver transplantation. Proteome Sci. 2007 Jan 2;5:1. Mass 

spectrometric analyses were performed by the platform 

37. Bergeron JJ, Hallett M. Peptides you can count on. Nat Biotechnol. 2007 Jan;25 (1): 61-2. Review 

38. Liu J, Bell AW, Bergeron JJ, Yanofsky CM, Carrillo B, Beaudrie CE, Kearney RE. Methods for 

peptide identification by spectral comparison. Proteome Sci. 2007 Jan 16;5:3. Mass spectrometric 


39. Warrick PA, Precup D, Hamilton EF, Kearney RE (2007) Fetal Heart Rate Deceleration Detection 

using a Discrete Cosine Transform Implementation of Singular Spectrum Analysis. Methods of 

Information in Medicine. 46:196-201 

40. Bell AW, Nilsson T, Kearney RE, Bergeron JJ (2007) The protein microscope: incorporating mass 

spectrometry into cell biology. Nat Methods 4: 783-784. 

41. Dziong D, Bagnaninchi PO, Kearney RE, Tabrizian M (2007) Nondestructive Online In Vitro 

Monitoring of Pre-Osteoblast Cell Proliferation Within Microporous Polymer Scaffolds, IEEE 

Transactions on Nanobioscience 6: 249-258 

42. Bergeron JJ, Bradshaw RA (2007) What has proteomics accomplished? Mol Cell Proteomics. 6: 

1824-1826. 

43. Au CE, Bell AW, Gilchrist A, Hiding J, Nilsson T, Bergeron JJ (2007) Organellar proteomics to 

create the cell map. Curr Opin Cell Biol 19: 376-385. 

44. Vercauteren FG, Flores G, Ma W, Chabot JG, Geenen L, Clerens S, Fazel A, Bergeron JJ, 

Srivastava LK, Arckens L, Quirion R.2007. An organelle proteomic method to study 

neurotransmission-related proteins, applied to a neurodevelopmental model of schizophrenia. 

Proteomics 7: 3569-3579. 


45. Makarenkov V, Zentilli P, Kevorkov D, Gagarin A, Malo N, Nadon R. 2007. An efficient method for 

the detection and elimination of systematic error in high-throughput screening. Bioinformatics. 2007 

Jul 1;23(13):1648-57. Epub 2007 Apr 26. 

46. Ferretti V, Poitras C, Bergeron D, Coulombe B, Robert F, Blanchette M. PReMod: a database of 

genome-wide mammalian cis-regulatory module predictions. Nucleic Acids Res. 2007 

Jan;35(Database issue):D122-6. Program developed by the bioinformatics platform 

47. Coulombe-Huntington J, Majewski J. (2007) Characterization of intron loss events in mammals. 

Genome Res 17: 23-32. 

48. Coulombe-Huntington J, Majewski J (2007) Intron loss and gain in Drosophila. Mol Biol Evol 24: 

2842-2850. 

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50. Chen X, Blanchette M (2007) Prediction of tissue-specific cis-regulatory modules using Bayesian 

networks and regression trees, BMC Bioinformatics 8 (Suppl10): S2. 

51. Jeronimo C, Forget D, Bouchard A, Li Q, Chua G, Poitras C, Thérien C, Bergeron D, Bourassa S, 

Greenblatt J, Chabot B, Poirier GG, Hughes TR, Blanchette M, Price DH, Coulombe B 

(2007) Systematic analysis of the protein interaction network for the human transcription machinery 

reveals the identity of the 7SK capping enzyme. Mol Cell 27: 262-274. 

52. Diallo AB, Makarenkov V, Blanchette M (2007) Exact and heuristic algorithms for the Indel Maximum 

Likelihood Problem. J Comput Biol 14: 446-461. 

53. Blin G, Blais E, Hermelin D, Guillon P, Blanchette M, and El-Mabrouk N (2007) Gene maps 

linearization using genomic rearrangement distances. J Comput Biol 14: 394-407. 

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Genomics Hum Genet 8: 193-213. 

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Gosline SJ, Hallett M, Paiement J, Kearney RE, Nilsson T, Bergeron JJ. Quantitative proteomics 

analysis of the secretory pathway. Cell 2006 Dec 15; 127 (6): 1265-81. Mass spectrometric analyses 

were performed by the platform 

2. Montpetit A, Chagnon F. The Haplotype Map of the human genome: a revolution in the genetics of 

complex diseases Med Sci (Paris) 2006 Dec;22 (12): 1061-7. Review 

3. Tremblay K, Lemire M, Provost V, Pastinen T, Renaud Y, Sandford AJ, Laviolette M, Hudson TJ, 

Laprise C. Association study between the CX3CR1 gene and asthma. Genes Immun. 2006 Dec;7 (8): 

632-9. Genotyping and sequencing were performed by the platform 

4. Hrebicek M, Mrazova L, Seyrantepe V, Durand S, Roslin NM, Noskova L, Hartmannova H, Ivanek R, 

Cizkova A, Poupetova H, Sikora J, Urinovska J, Stranecky V, Zeman J, Lepage P, Roquis D, Verner 

A, Ausseil J, Beesley CE, Maire I, Poorthuis BJ, van de Kamp J, van Diggelen OP, Wevers RA, 

Hudson TJ, Fujiwara TM, Majewski J, Morgan K, Kmoch S, Pshezhetsky AV. Mutations in 

TMEM76* cause mucopolysaccharidosis IIIC (Sanfilippo C syndrome). Am J Hum Genet. 2006 

Nov;79 (5): 807-19. Sequencing was performed by the platform 

5. Bailey SD, Loredo-Osti JC, Lepage P, Faith J, Fontaine J, Desbiens KM, Hudson TJ, Bouchard C, 

Gaudet D, Perusse L, Vohl MC, Engert JC. Common polymorphisms in the promoter of the visfatin 

gene (PBEF1) influence plasma insulin levels in a French-Canadian population. Diabetes 2006 

Oct;55 (10): 2896-902. Sequencing was performed by the platform. 

6. Thompson MD, Takasaki J, Capra V, Rovati GE, Siminovitch KA, Burnham WM, Hudson TJ, Bosse 

Y, Cole DE. G-protein-coupled receptors and asthma endophenotypes: the cysteinyl leukotriene 

system in perspective. Mol Diagn Ther. 2006;10 (6): 353-66. Genotyping was performed by the 

platform 

7. Qu HQ, Lawrence SG, Guo F, Majewski J, Polychronakos C. Strand bias in complementary singlenucleotide 

polymorphisms of transcribed human sequences: evidence for functional effects of 

synonymous polymorphisms. BMC Genomics 2006 Aug 17; 7: 213. Genotyping was performed by 

the platform 

8. Miron M, Woody OZ, Marcil A, Murie C, Sladek R, Nadon R. A methodology for global validation of 

microarray experiments. BMC Bioinformatics 2006 Jul 5; 7: 333. Expression arrays used were 

performed by the platform. 

9. Lu Y, Ponton A, Okamoto H, Takasawa S, Herrera PL, Liu JL. Activation of the Reg family genes by 

pancreatic-specific IGF-I gene deficiency and after streptozotocin-induced diabetes in mouse 

pancreas. Am J Physiol Endocrinol Metab. 2006 Jul;291 (1): E50-8. Expression arrays used were 

performed by the platform 

10. Emadali A, Muscatelli-Groux B, Delom F, Jenna S, Boismenu D, Sacks DB, Metrakos PP, Chevet E. 

Proteomic analysis of ischemia-reperfusion injury upon human liver transplantation reveals the 

protective role of IQGAP1. Mol Cell Proteomics 2006 Jul;5 (7): 1300-13. Mass spectrometric analyses 

were performed by the platform 

11. Sinnett D, Beaulieu P, Belanger H, Lefebvre JF, Langlois S, Theberge MC, Drouin S, Zotti C, 

Hudson TJ, Labuda D. Detection and characterization of DNA variants in the promoter regions of 

hundreds of human disease candidate genes. Genomics 2006 Jun;87 (6): 704-10. Sequencing was 



12. Montpetit A, Phillips MS, Mongrain I, Lemieux R, St-Louis M. High-throughput molecular profiling of 

blood donors for minor red blood cell and platelet antigens. Transfusion 2006 May;46 (5): 841-8. 

Assay design, genotyping and analyses were performed by the platform 

13. Sladek R, Hudson TJ. Elucidating cis- and trans-regulatory variation using genetical genomics. 

Trends Genet. 2006 May;22 (5): 245-50. Review 

14. Blanchette M, Bataille AR, Chen X, Poitras C, Laganiere J, Lefebvre C, Deblois G, Giguere V, 

Ferretti V, Bergeron D, Coulombe B, Robert F. Genome-wide computational prediction of 

transcriptional regulatory modules reveals new insights into human gene expression. Genome Res. 

2006 May;16 (5): 656-68. Part of the analysis was performed by the platform 

15. Mader S, Neculcea J, Neculcea V, Sladek R. Lipopolysaccharide and TNF-alpha produce very 

similar changes in gene expression in human endothelial cells. J Vasc Res. 2006;43 (5): 447-61. 

Expression arrays were performed by the platform 

16. Pastinen T, Ge B, Hudson TJ. Influence of human genome polymorphism on gene expression. Hum 

Mol Genet. 2006 Apr 15;15 Spec No 1:R9-16. Sequencing and RNA analyses were performed by the 

platform 

17. Hollmann CA, Owens T, Nalbantoglu J, Hudson TJ, Sladek R. Constitutive activation of extracellular 

signal-regulated kinase predisposes diffuse larGe B-cell lymphoma cell lines to CD40-mediated cell 

death. Cancer Res. 2006 Apr 1;66 (7): 3550-7. Expression arrays were performed by the platform 

18. Hudson TJ. Skin barrier function and allergic risk. Nature Genetics 2006 Apr;38 (4): 399-400. Review 

19. Lee PD, Ge B, Greenwood CM, Sinnett D, Fortin Y, Brunet S, Fortin A, Takane M, Skamene E, 

Pastinen T, Hallett M, Hudson TJ, Sladek R. Mapping cis-acting regulatory variation in recombinant 

congenic strains. Physiol Genomics 2006 Apr 13;25 (2): 294-302. Expression arrays were performed 

by the platform 

20. Guilbault C, Novak JP, Martin P, Boghdady ML, Saeed Z, Guiot MC, Hudson TJ, Radzioch D. 

Distinct pattern of lung gene expression in the Cftr-KO mice developing spontaneous lung disease 

compared with their littermate controls. Physiol Genomics 2006 Apr 13;25 (2): 179-93. Expression 

arrays were performed by the platform 

21. Le Page C, Ouellet V, Madore J, Hudson TJ, Tonin PN, Provencher DM, Mes-Masson AM. From 

gene profiling to diagnostic markers: IL-18 and FGF-2 complement CA125 as serum-based markers 

in epithelial ovarian cancer. Int J Cancer 2006 Apr 1;118 (7): 1750-8. Expression arrays were 


22. Montpetit A, Nelis M, Laflamme P, Magi R, Ke X, Remm M, Cardon L, Hudson TJ, Metspalu A. An 

evaluation of the performance of tag SNPs derived from HapMap in a Caucasian population. PLoS 

Genet. 2006 Mar;2(3): e27. Genotyping and most of the analyses were performed by the platform 

23. Lerner-Ellis JP, Gradinger AB, Watkins D, Tirone JC, Villeneuve A, Dobson CM, Montpetit A, 

Lepage P, Gravel RA, Rosenblatt DS. Mutation and biochemical analysis of patients belonging to the 

cblB complementation class of vitamin B12-dependent methylmalonic aciduria. Mol Genet Metab. 

2006 Mar;87 (3): 219-25. Sequencing was performed by the platform 

24. Saarela J, Kallio SP, Chen D, Montpetit A, Jokiaho A, Choi E, Asselta R, Bronnikov D, Lincoln MR, 

Sadovnick AD, Tienari PJ, Koivisto K, Palotie A, Ebers GC, Hudson TJ, Peltonen L. PRKCA and 

multiple sclerosis: association in two independent populations. PLoS Genet. 2006 Mar;2(3): e42. 

Genotyping was performed by the platform 


25. Le Page C, Ouellet V, Madore J, Ren F, Hudson TJ, Tonin PN, Provencher DM, Mes-Masson AM. 

Gene expression profiling of primary cultures of ovarian epithelial cells identifies novel molecular 

classifiers of ovarian cancer. Br J Cancer 2006 Feb 13;94 (3): 436-45. Expression arrays were 


26. Li C, Baquiran G, Gu F, Tremblay ML, Fazel A, Bergeron JJ, Posner BI. Insulin receptor kinaseassociated 

phosphotyrosine phosphatases in hepatic endosomes: assessing the role of 

phosphotyrosine phosphatase-1B. Endocrinology 2006 Feb;147 (2): 912-8. Mass spectrometric 


27. Tessier MC, Qu HQ, Frechette R, Bacot F, Grabs R, Taback SP, Lawson ML, Kirsch SE, Hudson 

TJ, Polychronakos C. Type 1 diabetes and the OAS gene cluster: association with splicing 

polymorphism or haplotype? J Med Genet. 2006 Feb;43 (2): 129-32. Genotyping and some analyses 

was performed by the platform 

28. Worgan LC, Niles K, Tirone JC, Hofmann A, Verner A, Sammak A, Kucic T, Lepage P, Rosenblatt 

DS. Spectrum of mutations in mut methylmalonic acidemia and identification of a common Hispanic 

mutation and haplotype. Hum Mutat. 2006 Jan;27 (1): 31-43. Sequencing was performed by the 

platform 

29. Serre D, Hudson TJ. Resources for genetic variation studies. Annu Rev Genomics Hum Genet. 

2006;7: 443-57. Review 

30. Lerner-Ellis JP, Tirone JC, Pawelek PD, Dore C, Atkinson JL, Watkins D, Morel CF, Fujiwara TM, 

Moras E, Hosack AR, Dunbar GV, Antonicka H, Forgetta V, Dobson CM, Leclerc D, Gravel RA, 

Shoubridge EA, Coulton JW, Lepage P, Rommens JM, Morgan K, Rosenblatt DS. Identification of 

the gene responsible for methylmalonic aciduria and homocystinuria, cblC type. Nature Genetics 

2006 Jan;38 (1): 93-100. Erratum in: Nature Genetics 2006 Aug;38 (8): 957. Sequencing was 


31. Loo VG, Poirier L, Miller MA, Oughton M, Libman MD, Michaud S, Bourgault AM, Nguyen T, Frenette 

C, Kelly M, Vibien A, Brassard P, Fenn S, Dewar K, Hudson TJ, Horn R, Rene P, Monczak Y, 

Dascal A. A predominantly clonal multi-institutional outbreak of Clostridium difficile-associated 

diarrhea with high morbidity and mortality. N Engl J Med. 2005 Dec 8;353 (23): 2442-9. Erratum in: N 

Engl J Med. 2006 May 18;354 (20): 2200. Part of the analysis was performed by the platform 

32. Zody MC, Garber M, Adams DJ, Sharpe T, Harrow J, Lupski JR, Nicholson C, Searle SM, Wilming L, 

Young SK, Abouelleil A, Allen NR, Bi W, Bloom T, Borowsky ML, Bugalter BE, Butler J, Chang JL, 

Chen CK, Cook A, Corum B, Cuomo CA, de Jong PJ, DeCaprio D, Dewar K, FitzGerald M, Gilbert J, 

Gibson R, Gnerre S, Goldstein S, Grafham DV, Grocock R, Hafez N, Hagopian DS, Hart E, Norman 

CH, Humphray S, Jaffe DB, Jones M, Kamal M, Khodiyar VK, LaButti K, Laird G, Lehoczky J, Liu X, 

Lokyitsang T, Loveland J, Lui A, Macdonald P, Major JE, Matthews L, Mauceli E, McCarroll SA, 

Mihalev AH, Mudge J, Nguyen C, Nicol R, O'Leary SB, Osoegawa K, Schwartz DC, Shaw-Smith C, 

Stankiewicz P, Steward C, Swarbreck D, Venkataraman V, Whittaker CA, Yang X, Zimmer AR, 

Bradley A, Hubbard T, Birren BW, Rogers J, Lander ES, Nusbaum C. (2006) DNA sequence of 

human chromosome 17 and analysis of rearrangement in the human lineage.Nature. 2006 Apr 

20;440(7087):1045-9. 

33. Zody MC, Garber M, Sharpe T, Young SK, Rowen L, O'Neill K, Whittaker CA, Kamal M, Chang JL, 

Cuomo CA, Dewar K, FitzGerald MG, Kodira CD, Madan A, Qin S, Yang X, Abbasi N, Abouelleil A, 

Arachchi HM, Baradarani L, Birditt B, Bloom S, Bloom T, Borowsky ML, Burke J, Butler J, Cook A, 

DeArellano K, DeCaprio D, Dorris L 3rd, Dors M, Eichler EE, Engels R, Fahey J, Fleetwood P, 

Friedman C, Gearin G, Hall JL, Hensley G, Johnson E, Jones C, Kamat A, Kaur A, Locke DP, Madan 

A, Munson G, Jaffe DB, Lui A, Macdonald P, Mauceli E, Naylor JW, Nesbitt R, Nicol R, O'Leary SB, 

Ratcliffe A, Rounsley S, She X, Sneddon KM, Stewart S, Sougnez C, Stone SM, Topham K, Vincent 


D, Wang S, Zimmer AR, Birren BW, Hood L, Lander ES, Nusbaum C. Analysis of the DNA sequence 

and duplication history of human chromosome 15. Nature. 2006 Mar 30;440(7084):671-5. 

34. Taylor TD, Noguchi H, Totoki Y, Toyoda A, Kuroki Y, Dewar K, Lloyd C, Itoh T, Takeda T, Kim DW, 

She X, Barlow KF, Bloom T, Bruford E, Chang JL, Cuomo CA, Eichler E, FitzGerald MG, Jaffe DB, 

LaButti K, Nicol R, Park HS, Seaman C, Sougnez C, Yang X, Zimmer AR, Zody MC, Birren BW, 

Nusbaum C, Fujiyama A, Hattori M, Rogers J, Lander ES, Sakaki Y. Human chromosome 11 DNA 

sequence and analysis including novel gene identification. Nature. 2006 Mar 23;440(7083):497-500. 

35. Nusbaum C, Mikkelsen TS, Zody MC, Asakawa S, Taudien S, Garber M, Kodira CD, Schueler MG, 

Shimizu A, Whittaker CA, Chang JL, Cuomo CA, Dewar K, FitzGerald MG, Yang X, Allen NR, 

Anderson S, Asakawa T, Blechschmidt K, Bloom T, Borowsky ML, Butler J, Cook A, Corum B, 

DeArellano K, DeCaprio D, Dooley KT, Dorris L 3rd, Engels R, Glöckner G, Hafez N, Hagopian DS, 

Hall JL, Ishikawa SK, Jaffe DB, Kamat A, Kudoh J, Lehmann R, Lokitsang T, Macdonald P, Major JE, 

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Venkataraman V, Wen G, Yamazaki S, Young SK, Zeng Q, Zimmer AR, Rosenthal A, Birren BW, 

Platzer M, Shimizu N, Lander ES. DNA sequence and analysis of human chromosome 8. Nature. 

2006 Jan 19;439(7074):331-5. 

36. Novak JP, Kim SY, Xu J, Modlich O, Volsky DJ, Honys D, Slonczewski JL, Bell DA, Blattner FR, 

Blumwald E, Boerma M, Cosio M, Gatalica Z, Hajduch M, Hidalgo J, McInnes RR, Miller MC 3rd, 

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polymorphism assay to diagnose the genomic identity of poplar species and hybrids on the Canadian 

prairies. Canadian Journal of Forest Research, 41:(5) 1102-1111. 

104. Girard S, Gauthier J, Noreau A, Xiong L, Zhou S, Jouan L, Dionne-Laporte A, Spiegelman D, 

Henrion E, Diallo O, Thibodeau P, Bachand I, Bao JYJ, Tong AHY, Lin CH, Millet B, Jaafari N, Joober 


R, Dion PA, Lok S, Krebs MO, Rouleau GA. Increased exonic de novo mutation rate in individuals 

with schizophrenia. July 2011. Nature Genetics – Volume 43 – 860-863 – DOI:10. 1038/ng.886. 


2010 

MPS 

1. Boon E, Zimmerman E, Lang BF, Hijri M. 2010. Intra-isolate genome variation in arbuscular 

mycorrhizal fungi persists in the transcriptome. J Evol Biol. 2010 Jul;23(7):1519-27. Epub 2010 Jun 4. 

2. Hancock L, Goff L, Lane C. 2010. Red Algae Lose Key Mitochondrial Genes In Response To 

Becoming Parasitic. Genome Biol Evol. 2010 Nov 15. [Epub ahead of print] 

3. Pombert JF, Keeling PJ. 2010. The mitochondrial genome of the entomoparasitic green alga 

helicosporidium PLoS One 5(1) 

4. Zaikova E, Walsh DA, Stilwell CP, Mohn WW, Tortell PD, Hallam SJ. 2010. Microbial community 

dynamics in a seasonally anoxic fjord: Saanich Inlet, British Columbia. Environ Microbiol. 2010 

Jan;12(1):172-91. Epub 2009 Sep 24. 

5. Renaut S, Nolte AW, Bernatchez L. 2010. Mining transcriptome sequences toward identifying 

adaptive single nucleotide polymorphisms in lake whitefish species pairs (Coregonus spp. 

Salmonidae) Molecular Ecology 19(1): 115-131. 

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6. Lanktree MB, Johansen CT, Anand SS, Davis AD, Miller R, Yusuf S, Hegele RA; SHARE 

Investigators; SHARE-AP Investigators. 2010. Genetic variation in hyaluronan metabolism loci is 

associated with plasma plasminogen activator inhibitor-1 concentration. Blood. 2010 Sep 

23;116(12):2160-3. Epub 2010 Jun 17. 

7. Hosein AN, Wu M, Arcand SL, Lavallée S, Hébert J, Tonin PN, Basik M. 2010. Breast carcinomaassociated 

fibroblasts rarely contain p53 mutations or chromosomal aberrations. Cancer Res. 2010 

Jul 15;70(14):5770-7. Epub 2010 Jun 22. 

8. Guernsey DL, Dubé MP, Jiang H, Asselin G, Blowers S, Evans S, Ferguson M, Macgillivray C, 

Matsuoka M, Nightingale M, Rideout A, Delatycki M, Orr A, Ludman M, Dooley J, Riddell C, Samuels 

ME. 2010. Novel mutations in the sacsin gene in ataxia patients from Maritime Canada. J Neurol Sci. 

2010 Jan 15;288(1-2):79-87. 

9. Guernsey DL, Jiang H, Bedard K, Evans SC, Ferguson M, Matsuoka M, Macgillivray C, Nightingale 

M, Perry S, Rideout AL, Orr A, Ludman M, Skidmore DL, Benstead T, Samuels ME. 2010. Mutation 

in the gene encoding ubiquitin ligase LRSAM1 in patients with Charcot-Marie-Tooth disease. PLoS 

Genet. 2010 Aug 26;6(8). pii: e1001081. 

10. Guernsey DL, Jiang H, Hussin J, Arnold M, Bouyakdan K, Perry S, Babineau-Sturk T, Beis J, Dumas 

N, Evans SC, Ferguson M, Matsuoka M, Macgillivray C, Nightingale M, Patry L, Rideout AL, Thomas 

A, Orr A, Hoffmann I, Michaud JL, Awadalla P, Meek DC, Ludman M, Samuels ME. 2010. Mutations 

in centrosomal protein CEP152 in primary microcephaly families linked to MCPH4. Am J Hum Genet. 

2010 Jul 9;87(1):40-51 

11. Hubert S, Higgins B, Borza T, Bowman S. 2010. Development of a SNP resource and a genetic 

linkage map for Atlantic Cod (Gadus Morhua) BMC Genomics 11(191): . 

12. Bradbury IR, Hubert S, Higgins B, Borza T, Bowman S, Paterson IG, Snelgrove PV, Morris CJ, 

Gregory RS, Hardie DC, Hutchings JA, Ruzzante DE, Taggart CT, Bentzen P. 2010. Parallel adaptive 

evolution of Atlantic cod on both sides of the Atlantic Ocean in response to temperature. Proc Biol 

Sci. 2010 Dec 22;277(1701):3725-34. Epub 2010 Jun 30. 


13. Bernard G, Thiffault I, Tetreault M, Putorti ML, Bouchard I, Sylvain M, Melançon S, Laframboise R, 

Langevin P, Bouchard JP, Vanasse M, Vanderver A, Sébire G, Brais B. 2010. Tremor-ataxia with 

central hypomyelination (TACH) leukodystrophy maps to chromosome 10q22.3-10q23.31. 

Neurogenetics. 2010 Oct;11(4):457-64. Epub 2010 Jul 17. 

14. Tremblay J, Déziel E. 2010. Gene expression in Pseudomonas aeruginosa swarming motility. BMC 

Genomics. 2010 Oct 20;11:587. 

15. Simeone SM, Li MW, Paradis P, Schiffrin EL. 2010. Vascular gene expression in mice 

overexpressing human endothelin-1 targeted to the endothelium. Physiol Genomics. 2010 Nov 2. 

16. Tournas A, Mfuna L, Bossé Y, Filali-Mouhim A, Grenier JP, Desrosiers M. 2010. A pooling-based 

genome-wide association study implicates the p73 gene in chronic rhinosinusitis. J Otolaryngol Head 

Neck Surg. 2010 Apr;39(2):188-95. 

17. Hamzeh M, Robaire B. 2010. Identification of early response genes and pathway activated by 

androgens in the initial segment and caput regions of the regressed rat epididymis. Endocrinology. 

2010 Sep;151(9):4504-14. Epub 2010 Jul 21. 

18. Tremblay AM, Dufour CR, Gharhemani M, Reudelhuber TL, Giguere V. 2010. Physiological genomics 

identifies estrogen-related receptor α as a regulator of renal sodium and potassium homeostasis and 

the renin-angiotensin pathway. Molecular Endocrinology 24(1): 22-32. 

19. Bouchard L, Rabasa-Lhoret R, Faraj M, Lavoie ME, Mill J, Perusse L, Vohl MC. 2010. Differential 

epigenomic and transcriptomic responses in subcutaneous adipose tissue between low and high 

responders to caloric restriction. Am. J. Clin. Nutrition 91(2): 309-320. 

20. Normandin K, Peant B, Le Page C, de Ladurantaye M, Ouellet V, Tonin PM, Provencher DM, Mes- 

Masson AM. 2010. Protease inhibitor SERPINA1 expression in epithelial ovarian cancer. Clinical and 

Experimental Metastasis 27(1): online. 

21. Bolduc V, Marlow G, Boycott K, Saleki K, Innoue H, Kroon J, Itakura M, Robitaille Y, Parent L, Baas 

F. 2010. Recessive mutations in the putative callcium-activated chloride channel anoctamine 5 cause 

proximal LGMD2L and distal MMD3 muscular distrophies. Am. J. Hum. Genet. 86(2): 213-221 

22. Voisin V, Legault P, Salazar Ospina DP, Ben-David Y, Rassart E. 2010. Gene profiling of the erythroand 

megakaryoblastic leukaemias induced by the Graffi murine retrovirus. BMC Medical Genomics 3: 

2. 

23. Suvorov A, Takser L. 2010. Global Gene Expression Analysis in the Livers of Rat Offspring 

Perinatally Exposed to Low Doses of 2,2’,4,4’-Tetrabromodiphenyl Ether Environmental Health 

Perspectives 118(1): . 

24. Chari R, Coe BP, Vucic EA, Lockwood WW, Lam WL. 2010. An integrative multi-dimensional genetic 

and epigenetic strategy to identify aberrant genes and pathways in cancer. BMC Systems Biology 4: 

67. 

25. Tadevosyan A, Maguy A, Villeneuve LR, Babin J, Bonnefoy A, Allen BG, Nattel S. 2010. Nucleardelimited 

angiotensin receptor-mediated signaling regulates cardiomyocyte gene expression. Journal 

of Biological Chemistry 285: 22338-49. 

26. Meunier L, Puiffe ML, Le Page C, Filali-Mouhim A, Chevrette M, Tonin PN, Provencher DM, Mes- 

Masson AM. 2010. Effect of ovarian cancer ascites on cell migration and gene expression in an 

epithelial ovarian cancer in vitro model. Transl Oncol. 2010 Aug 1;3(4):230-8. 


27. Yu H, Mashtalir N, Daou S, Hammond-Martel I, Ross J, Sui G, Hart GW, Rauscher FJ 3rd, Drobetsky 

E, Milot E, Shi Y, Affar el B. 2010. The ubiquitin carboxyl hydrolase BAP1 forms a ternary complex 

with YY1 and HCF-1 and is a critical regulator of gene expression. Mol Cell Biol. 2010 

Nov;30(21):5071-85. Epub 2010 Aug 30. 

28. Amin Kerachian M, Cournoyer D, Harvey EJ, Chow TY, Bégin LR, Nahal A, Séguin C. 2010. New 

insights into the pathogenesis of glucocorticoid-induced avascular necrosis: microarray analysis of 

gene expression in a rat model. Arthritis Res Ther. 2010;12(3):R124. Epub 2010 Jun 25. 

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29. Di Paola D, Rampakakis E, Chan MK, Arvanitis DN, Zannis-Hadjopoulos M. 2010. Increased origin 

activity in transformed versus normal cells: identification of novel protein players involved in DNA 

replication and cellular transformation. Nucleic Acids Res. 2010 Apr;38(7):2314-31. Epub 2010 Jan 

11. 

30. Ibeagha-Awemu EM, Ibeagha AE, Messier S, Zhao X. 2010. Proteomics, genomics, and pathway 

analyses of Escherichia coli and Staphylococcus aureus infected milk whey reveal molecular 

pathways and networks involved in mastitis. J Proteome Res. 2010 Sep 3;9(9):4604-19. 

31. Hammami W, Chain F, Michaud D, Belanger RR. 2010. Proteomic analysis of the metabolic 

adaptation of the biocontrol agent Pseudozyma flocculosa leading to glycolipid production. Proteome 

Science 8(7): . 

32. Marsolais F, Pajak A, Yin F, Taylor M, Gabriel M, Merino DM, Ma V, Kameka A, Vijayan P, Pham H, 

Huang S, Rivoal J, Bett K, Hernández-Sebastià C, Liu Q, Bertrand A, Chapman R. (2010) Proteomic 

analysis of common bean seed with storage protein deficiency reveals up-regulation of sulfur-rich 

proteins and starch and raffinose metabolic enzymes, and down-regulation of the secretory pathway. 

J. Proteomics 73: 1587-1600. 

33. Halawani D, Tessier S, Anzellotti D, Bennett DA, Latterich M, LeBlanc AC. 2010. Identification of 

Caspase-6-mediated processing of the valosin containing protein (p97) in Alzheimer's disease: a 

novel link to dysfunction in ubiquitin proteasome system-mediated protein degradation. J Neurosci. 

2010 Apr 28;30(17):6132-42. 

34. Maher-Laporte, M., Berthiaume, F., Moreau, M., Julien, L.-A., Lapointe, G., Mourez, M., and 

DesGroseillers, L. (2010) Molecular composition of Staufen2-containing ribonucleoproteins in 

embryonic rat brain. PlosOne 5, e11350 

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35. Amre DK, Mack DR, Morgan K, Israel D, Deslandres C, Seidman EG, Lambrette P, Costea I, 

Krupoves A, Fegury H, Dong J, Xhu Z, Grimard G, Levy E. 2010. Association between genome-wide 

association studies reported SNPs and pediatric-onset Crohn's disease in Canadian children. Hum 

Genet. 2010 Aug;128(2):131-5. Epub 2010 May 16. 

36. Amre DK, Mack DR, Morgan K, Israel D, Deslandres C, Seidman EG, Lambrette P, Costea I, 

Krupoves A, Fegury H, Dong J, Grimard G, Levy E. 2010. Susceptibility loci reported in genome-wide 

association studies are associated with Crohn's disease in Canadian children. Aliment Pharmacol 

Ther. 2010 Jun;31(11):1186-91. Epub 2010 Mar 8. 

37. Ma RC, Tam CH, Wang Y, Luk AO, Hu C, Yang X, Lam V, Chan AW, Ho JS, Chow CC, Tong PC, Jia 

W, Ng MC, So WY, Chan JC. 2010. Genetic variants of the protein kinase C-beta 1 gene and 

development of end-stage renal disease in patients with type 2 diabetes. JAMA. 2010 Aug 

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38. Tam CH, Ho JS, Wang Y, Lee HM, Lam VK, Germer S, Martin M, So WY, Ma RC, Chan JC, Ng MC. 

2010. Common polymorphisms in MTNR1B, G6PC2 and GCK are associated with increased fasting 

plasma glucose and impaired beta-cell function in Chinese subjects. PLoS One. 2010 Jul 

8;5(7):e11428. 

39. Mong JL, Ng MC, Guldan GS, Tam CH, Lee HM, Ma RC, So WY, Wong GW, Kong AP, Chan JC, 

Waye MM. 2010. Associations of the growth hormone receptor (GHR) gene polymorphisms with 

adiposity and IGF-I activity in adolescents. Clin Endocrinol (Oxf). 2010 Sep;73(3):313-22. Epub 2010 

Jan 23. 

40. Kilty SJ, Bossé Y, Cormier C, Endam LM, Desrosiers MY. 2010. Polymorphisms in the SERPINA1 

(Alpha-1-Antitrypsin) gene are associated with severe chronic rhinosinusitis unresponsive to medical 

therapy. Am J Rhinol Allergy. 2010 Jan-Feb;24(1):e4-9. 

41. Endam LM, Cormier C, Bosse Y, Filali-Mouhim A, Desrosiers M. 2010. Association of IL1A, IL1B, and 

TNF Gene Polymorphisms With Chronic Rhinosinusitis With and Without Nasal Polyposis 

Otolaryngology - Head and Neck Surgery 136(2): 187-192. 

42. Damaraju S, Damaraju VL, Mowles D, Sawyer MB, Damaraju S, Cass CE. 2010. Cytotoxic activity of 

gemcitabine in cultured cell lines derived from histologically different types of bladder cancer: role of 

thymidine kinase 2. Biochem Pharmacol. 2010 Jan 1;79(1):21-9. Epub 2009 Aug 4. 

43. Tarabeux J, Champagne N, Brustein E, Hamdan FF, Gauthier J, Lapointe M, Maios C, Piton A, 

Spiegelman D, Henrion E; Synapse to Disease Team, Millet B, Rapoport JL, Delisi LE, Joober R, 

Fathalli F, Fombonne E, Mottron L, Forget-Dubois N, Boivin M, Michaud JL, Lafrenière RG, Drapeau 

P, Krebs MO, Rouleau GA. 2010. De novo truncating mutation in Kinesin 17 associated with 

schizophrenia. Biol Psychiatry. 2010 Oct 1;68(7):649-56. Epub 2010 Jun 19. 

44. Awadalla P, Gauthier J, Myers RA, Casals F, Hamdan FF, Griffing AR, Côté M, Henrion E, 

Spiegelman D, Tarabeux J, Piton A, Yang Y, Boyko A, Bustamante C, Xiong L, Rapoport JL, 

Addington AM, DeLisi JL, Krebs MO, Joober R, Millet B, Fombonne E, Mottron L, Zilversmit M, 

Keebler J, Daoud H, Marineau C, Roy-Gagnon MH, Dubé MP, Eyre-Walker A, Drapeau P, Stone EA, 

Lafrenière RG, Rouleau GA. 2010. Direct measure of the de novo mutation rate in autism and 

schizophrenia cohorts. Am J Hum Genet. 2010 Sep 10;87(3):316-24. 

45. Gauthier J, Champagne N, Lafreniere RG, Xiong L, Spiegelman D, Brustein E, Lapointe M, Peng H, 

Cote M, Noreau A, Hamdan FF, Addington AM, Rapoport JL, DeLisi LE, Krebs MO, Joober R, Fathalli 

F, Mouaffak F, Haghighi AP, Neri C, Dube MP, Samuels ME, Marineau C, Stone EA, Awadalla P, 

Barker PA, Carbonetto S, Drapeau P, Rouleau GA, S2D Team. 2010. De novo mutations in the gene 

encoding the synaptic scaffolding protein SHANK3 in patients ascertained for schizophrenia PNAS 

107(17): 7863-7868. 

46. Piton A, Gauthier J, Hamdan FF, Lafreniere RG, Yang Y, Henrion E, Laurent S, Noreau A, Thibodeau 

P, Karemera L, Spiegelman D, Kuku F, Duguay J, Destroismaisons L, Jolivet P, Cote M, Lachapelle 

K, Diallo O, Raymond A, Marineau C, Champagne N, Xiong L, Gaspar C, Riviere JB, Tarabeux J, 

Cossette P, Krebs MO, Rapoport JL, Addington A, DeLisi LE, Mottron L, Joober R, Fombonne E, 

Drapeau P, Rouleau GA. 2010. Systematic resequencing of X-chromosome synaptic genes in autism 

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47. Hamdan FF, Daoud H, Rochefort D, Piton A, Gauthier J, Langlois M, Foomani G, Dobrzeniecka S, 

Krebs MO, Joober R, Lafrenière RG, Lacaille JC, Mottron L, Drapeau P, Beauchamp MH, Phillips 

MS, Fombonne E, Rouleau GA, Michaud JL. 2010. De novo mutations in FOXP1 in cases with 

intellectual disability, autism, and language impairment. Am J Hum Genet. 2010 Nov 12;87(5):671-8. 

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48. Christine, GST, Germaine P, Bogaty L, Boyer J, Hanley JC, Engert JC, Brophy JM. 2010. Genetic 

Polymorphisms and the Cardiovascular Risk of Non-Steroidal Anti-Inflammatory Drugs The American 

Journal of Cardiology 105(12): 1740-1745. 

49. Leiva-Torres GA, Rochette PA, Pearson A. 2010. Differential importance of highly conserved 

residues in UL24 for herpes simplex virus 1 replication in vivo and reactivation. J Gen Virol. 2010 

May;91(Pt 5):1109-16. Epub 2010 Jan 13. 

50. Gu WX, Kania A. 2010. Identification of genes controlled by LMX1B in E13.5 mouse limbs. Dev Dyn. 

2010 Aug;239(8):2246-55. 

51. Bergeron S, Lemieux E, Durand V, Cagnol S, Carrier JC, Lussier JG, Boucher MJ, Rivard N. 2010. 

The serine protease inhibitor serpinE2 is a novel target of ERK signaling involved in human colorectal 

tumorigenesis. Mol Cancer. 2010 Oct 13;9:271. 

52. Vassilenko EI, Muttray AF, Schulte PM, Baldwin SA. 2010. Variations in p53-like cDNA sequence are 

correlated with mussel haemic neoplasia: A potential molecular-level tool for biomonitoring. Mutat 

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53. Bourguinat C, Kamgno J, Boussinesq M, Mackenzie CD, Prichard RK, Geary TG. 2010. Analysis of 

the mdr-1 gene in patients co-infected with Onchocerca volvulus and Loa loa who experienced a 

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54. Oh-McGinnis R, Bogutz AB, Lee KY, Higgins MJ, Lefebvre L. 2010. Rescue of placental phenotype in 

a mechanistic model of Beckwith-Wiedemann syndrome. BMC Dev Biol. 2010 May 11;10:50. 

55. Dimitriu PA, Grayston SJ. 2010. Relationship between soil properties and patterns of bacterial betadiversity 

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56. Paun A, Fox J, Balloy V, Chignard M, Qureshi ST, Haston CK. 2010. Combined Tlr2 and Tlr4 

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57. Lamba P, Wang Y, Tran S, Ouspenskaia T, Libasci V, Hébert TE, Miller GJ, Bernard DJ. 2010. 

Activin A regulates porcine follicle-stimulating hormone beta-subunit transcription via cooperative 

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58. Mechaly AS, Viñas J, Murphy C, Reith M, Piferrer F. 2010. Gene structure of the Kiss1 receptor-2 

(Kiss1r-2) in the Atlantic halibut: insights into the evolution and regulation of Kiss1r genes. Mol Cell 

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59. Morris-Pocock JA, Taylor SA, Birt TP, Friesen VL. 2010. Concerted evolution of duplicated 

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60. Zhang TY, Hellstrom IC, Bagot RC, Wen X, Diorio J, Meaney MJ. 2010. Maternal care and DNA 

methylation of a glutamic acid decarboxylase 1 promoter in rat hippocampus. J Neurosci. 2010 Sep 

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61. Hagen KE, Tramp CA, Altermann E, Welker DL, Tompkins TA. 2010. Sequence analysis of plasmid 

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62. Domenech P, Kolly GS, Leon-Solis L, Fallow A, Reed MB. 2010. Massive gene duplication event 

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63. Afshar K, Dufresne PJ, Pan L, Merkx-Jacques M, Bede JC. 2010. Diet-specific salivary gene 

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64. Rogers SL, Zhao Y, Jiang X, Eaves CJ, Mager DL, Rouhi A. 2010. Expression of the leukemic 

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65. Zhao JS, Deng Y, Manno D, Hawari J. 2010. Shewanella spp. genomic evolution for a cold marine 

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66. Meury T, Akhouayri O, Jafarov T, Mandic V, St-Arnaud R. 2010. Nuclear αNAC influences bone 

matrix mineralization and osteoblast maturation In Vivo. Molecular and cellular biology 30(1): 43-53. 

67. Leiva-Torres GA, Rochette PA, Pearson A. 2010. Differential importance of highly conserved 

residues in UL24 for herpes simplex virus 1 replication in vivo and reaction. J. Gen. Virol. online: . 

68. Consaul LL, Gillespie LJ, Waterway MJ. 2010. Evolution and polyploid origins in North American 

arctic Puccinellia (Poaceae) based on nuclear ribosomal spacer and chloroplast DNA sequences. 

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69. Fallow A, Domenech P, Reed MB. 2010. Strains of the East Asian (W/Beijing) Lineage of 

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70. Said KB, Ismail J, Campbell J, Mulvey MR, Bourgault AM, Messier S, Zhao X. 2010. Regional 

Profiling for Determination of Genotype Diversity of Mastitis-Specific Staphylococcus aureus Lineage 

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71. Letourneau A, Seena S, Marvanova L, Barlocher F. 2010. Potential use of barcoding to identify 

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72. Doucet-Beaupre H, Breton S, Chapman EG, Blier PU, Bogan AE, Stewart DT, Hoeh WR. 2010. 

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73. Henley SA, Francis SM, Demone J, Ainsworth P, Dick FA. 2010. A cancer derived mutation in the 

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74. Haidara A, Chamberland A, Sylla M, Aboubacrine SA, Cisse M, Traore H, Maiga MY, Tounkara A, 

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75. Slotte T, Foxe JP, Hazzouri KM, Wright SI. 2010. Genome-wide evidence for efficient positive and 

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76. Bertrand L, Leiva-Torres GA, Hyjazie H, Pearson A. 2010. Conserved Residues in the UL24 Protein 

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77. Schulze-Makuch D, Haque S, de Sousa Antonio MR, Ali D, Hosein R, Song YC, Yang Y, Zaikova E, 

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78. De Koeyer D, Douglass K, Murphy A, Whitney S, Nolan L, Song Y, De Jong W. 2010. Application of 

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79. Daley JM, Wilson TE, Ramotar D. 2010. Genetic interactions between HNT3/Aprataxin and 

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2009 

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1. Mackenzie N, Alexander DC, Turenne CY, Behr MA, De Buck JM. (2009) Genomic comparison of PE 

and PPE genes in the Mycobacterium avium Complex. Journal of Clinical Microbiology 47: 1002- 

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2. Alexander DC, Turenne CY, Behr MA. (2009) Insertion and deletion events that define the pathogen 

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M, Nightingale M, Rideout A, Saint-Amant L, Schmidt PJ, Orr A, Bottomley SS, Fleming MD, Ludman 

M, Dyack S, Fernandez CV, Samuels ME. 2009. Mutations in mitochondrial carrier family gene 

SLC25A38 cause nonsyndromic autosomal recessive congenital sideroblastic anemia. Nat Genet. 

2009 Jun;41(6):651-3. 

5. Guernsey DL, Jiang H, Evans SC, Ferguson M, Matsuoka M, Nightingale M, Rideout AL, Provost S, 

Bedard K, Orr A, Dubé MP, Ludman M, Samuels ME. Mutation in pyrroline-5-carboxylate reductase 1 

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6. Berghout J, Min-Oo G, Tam M, Gauthier S, Stevenson MM, Gros P. 2009. Identification of a novel 

cerebral malaria susceptibility locus (Berr5) on mouse chromosome 19. Genes and Immunity online 

7. Garcia-Crespo D, Knock E, Jabado N, Rozen R. (2009) Intestinal neoplasia induced by low dietary 

folate is associated with altered tumor expression profiled and decreased apoptosis in mouse normal 

intestine. Nutrition and Disease 139: 488-494. 

8. Iatan I, Dastani Z, Do R, Weissglass D, Ruel I, Lee JC, Huertas-Vazquez A, Taskinen MT, Prat A, 

Seidah NG, Pajukanta P, Engert JC, Genest J. 2009. Genetic variation at the proprotein covertase 

subtilisin/kexin type 5 gene modulates HDL cholesterol levels. Circulation online. 

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interactions with Melampsora rust fungi. Mol Plant Microbe Interact. 2009 Feb;22(2):190-200. 

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macrophages in allergic asthma: an expression signature characterized by heat shock protein 

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12. Quinn MCJ, Wilson DJ, Young F, Dempsey AA, Arcand SL, Birch AH, Wojnarowicz PM, Provencher 

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14. Llamas B, Verdugo RA, Churchill GA, Deschepper CF (2009) Chromosome Y variants from different 

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15. Labrie V, Fukumura R, Rastogi A, Fick LJ, Wang W, Boutros PC, Kennedy JL, Semeralul MO, Lee 

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17. McGrath MF, de Bold AJ. (2009) Transcriptional analysis of the mammalian heart with special 

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28. Dallaire F, Blanchette P, Branton PE. 2009. A Proteomic Approach to Identify Candidate Substrates 

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33. Tewfik MA, Bossé Y, Lemire M, Hudson TJ, Vallée-Smejda S, Al-Shemari H, Laprise C, Desrosiers 

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36. Tam CH, Ma RC, So WY, Wang Y, Lam VK, Germer S, Martin M, Chan JC, Ng MC (2009) Interaction 

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41. H Daoud1, P N Valdmanis1, E Kabashi1, P Dion1, N Dupré2, W Camu3, V Meininger4, G A 

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42. Julie Gauthier 1, Dan Spiegelman 1, Amélie Piton 1, Ronald G. Lafrenière 1, Sandra Laurent 1, Judith 

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43. Duan K, Binkley K, Rouleau GA. (2009) Genetic analysis of Factor-XII and bradykinin catabolic 

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44. Edor Kabashi, PhD; Hussein Daoud, PhD; Jean-Baptiste Rivière, BSc; Paul N. Valdamanis, BSc; 

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46. Hamdan FF, Gauthier J, Pellerin S, Dobrzeniecka S, Marineau C, Fombonne E, Mottron L, 

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49. Trahan C, Dragon F (2009) Dyskeratosis congenita mutations in the H/ACA domain of human 

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50. Villion M, Chopin MC, Deveau H, Dusko Ehrlich S, Moineau S, Chopin A (2009) P087, a lactococcal 

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52. Sepehri S, Kotlowski R, Bernstein CN, Krause DO. (2009) Phylogenetic analysis of inflammatory 

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53. Chénier MR, Juteau P. (2009) Fate of chlortetracycline- and tylosin-resistant bacteria in an aerobic 

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54. Tremblay YD, Lo H, Li YH, Halperin SA, Lee SF (2009) Expression of the Streptococcus mutans 

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58. Cody NA, Shen Z, Ripeau JS, Provencher DM, Mes-Masson AM, Chevrette M, Tonin PN (2009) 

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59. Reed MB, Pichler VK, McIntosh F, Mattia A, Fallow A, Masala S, Domenech P, Zwerling A, Thibert L, 

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60. Zimmerman B, Simaan M, Lee MH, Luttrell LM, Laporte SA. (2009) c-Src-mediated phosphorylaltion 

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61. Lai CB, Zhang Y, Rogers SL, Mager DL. (2009) Creation of the two isoforms of rodent NKG2D was 

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63. Maksakova IA, Zhang Y, Mager DL. (2009) Preferential epigenetic suppression of the autonomous 

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66. Chatoo W, Abdouh M, David J, Champagne MP, Ferreira J, Rodier F, Bernier G. (2009) The 

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67. Niederberger TD, Perreault NN, Lawrence JR, Nadeau JL, Mielke RE, Greer CW, Andersen DT, 

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68. Kennah E, Ringrose A, Zhou LL, Esmailzadeh S, Qian H, Su MW, Zhou Y, Jiang X. (2009) 

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73. Lee-Yam JA, Davidson A, McRae BH, Green DM. 2009. Do lanscape processes predict 

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74. Said K, Ramotar K, Zhu G, Zhao X. 2009. Repeat-based subtyping and grouping of Staphylococcus 

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75. Liu N, Han H, Lasko P. 2009. Vasa promotes Drosophila germline stem cell differentiation by 

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76. Baum BR, Edwards T, Johnson DA. 2009. Phylogenetic relationships among diploid Aegilops species 

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78. Degagne E, Grbic DM, Dupuis AA, Lavoie EG, Langlois C, Jain N, Weisman GA, Sevigny J, Gendron 

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80. Del Duca D, Wong G, Trieu P, Rodaros D, Kouremenos A, Tadevosyan A, Vaniotis G, Villeneuve L, 

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ventricular gene expresion: an animal model. The Journal of Thoracic and Cardiovascular Surgery. 

138(3): 538-546. 

81. Mardis ER, Lunshof JE. 2009. A focus on personal genomics. Personalized Medicine 6(6): 603-606. 

82. Han B, Wu J. 2009. DcR3 protects islet β cells from apoptosis through modulating Adcyap 1 and 

Bank 1 expression. The Journal of Immunology 183: 8157-8166. 

83. Buscarlet M, Hermann R, Lo R, Tang Y, Joachim K, Stifani S. 2009. Co-factor activated 

phosphorylation is required for inhibition of cortical neuron differentiation by Groucho/TLE1 PLoS One 

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84. Cui W, Simaan M, Laporte S, Lodge R, Cianflone K. 2009. C5a- and ASP-mediated C5L2 activation, 

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85. Stojanovic, N. 2009. A study of the distribution of phylogenetically conserved blocks within clusters of 

mammalian homeobox genes. Genet. Mol. Biol. 32(3). 

86. Ching B, Jamieson S, Heath JW, Heath DD, Hubberstey A. 2009. Transcriptional differences between 

triploid and diploid Chinook salmon (Oncorynchus tshawytscha) during live Vibrio anguillarium 

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87. Powdrill MH, Deval J, Narjes F, De Francesco R, Gotte M. 2009. Mechanism of hepatitis C virus RNA 

polymerase inhibition with dihydroxypyrimidines. Antimicrobial Agents and Chemotherapy online. 

88. Arya G, Niven DF. 2010. Production of haemolysins by strains of the Actinobacillus 

minor/“porcitonsillarum” complex Veterinary Parasitology Volume 141, Issues 3-4, 24 March 2010, 

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relationship between polymorphisms and surface expression on monocytes and polymorphonuclear 

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45. Klaiman G, Petzke TL, Hammond J, Leblanc AC (2008) Targets of caspase-6 activity in human 

neurons and Alzheimer disease. Mol Cell Proteomics 7: 1541-1555. 

46. Tuason MC, Rastikerdar A, Kuhlmann T, Goujet-Zalc C, Zalc B, Dib S, Friedman H, Peterson A. 

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of its contribution to the risk of breast cancer in French Canadian women. BMC Cancer (8) 239-247. 

48. Arcand SL, Maugard CM, Ghadirian P, Robidoux A, Perret C, Zhang P, Fafard E, Mes-Masson AM, 

Foulkes WD, Provencher D, Narod SA, Tonin PN. (2008) Germline TP53 mutations in BRCA1 and 

BRCA2 mutation-negative French Canadian breast cancer families. Epidemiology (108): 399-408. 

49. Singh J, Savitch L, Subramaniam G, Allard G, Jordan M, Couroux P, Pandeya R, Kalikililo A, Dougals 

J. (2008) The GLK1 Regulon encodes disease defence related proteins and confers resistance to 

Fusarium Graminearum in Arapidopsis. Cereal Research Communications (36): 261-265. 

50. Baum BR, Johnson DA (2008) Molecular confirmation of the genomic constitution of Douglasdeweya 

(Triticeae: Poaceae): demonstration of the utility of the 5S rDNA sequence as a tool for haplome 

identification. Mol Genet Genomics 279: 621-628. 

51. Saadatmand J, Guo F, Cen S, Niu M, Kleiman L (2008) Interactions of reverse transcriptase 

sequences in Pol with Gag and LysRS in the HIV-1 tRNALys3 packaging/annealing complex. Virology 

380: 109-117. 

52. Loret S, Guay G, Lippé R (2008) Comprehensive characterization of extracellular herpes simplex 

virus type 1 virions. J Virol 82: 8605-8618. 


53. Tang X, Hou A, Babu M, Nguyen V, Hurtado L, Lu Q, Reyes JC, Wang A, Keller WA, Harada JJ, 

Tsang EW, Cui Y (2008) The Arabidopsis BRAHMA chromatin-remodeling ATPase is involved in 

repression of seed maturation genes in leaves. Plant Physiol. 147: 1143-1157. 

54. Perron JG, Bell G, Quessy S. (2008) Parallel evolution of multidrug resistance in Salmonella enterica 

isolated from swine. FEMS Microbiology Letters (281): 17-22. 

55. Morrissette DC, Dauch A, Beech R, Masson L, Brousseau R, Jabaji-Hare S. (2008) Isolation of 

micoparasitic-related transcripts by SSH during interaction of the mycoparasite Stachybotris elegans 

with its host Rhizoctonia solani. Current Genetics (53): 67-80. 

56. McNamara S, Wang H, Hanna N, Miller WH. (2008) Topoisomerase IIβ negatively modulates acid 

receptor α function: a novel mechanism of retinoic acid resistance. MCB (28): 2066-2077. 

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and Le3 regulate gene expression in vegetative tissues in Arapidopsis. Plant Science (175):868-876. 

58. Lamarche MG, Kim SH, Crepin S, Mourez M, Bertrand N, Bishop RE, Dubreuil JD, Harel J. (2008) 

Modulation of Hexa-Acyl pyrophosphate lipid A population under Escherichia coli Phosphate (Pho) 

regulon activation. J. Bacteriology (190): 5256-5264. 

59. Mottier ML, Prichard RK. (2008) Genetic analysis of a relationship between macrocyclic lactone and 

benzimidazole anthelmintic selection on Haemonchus contortus. Pharmacogenetics and Genomics 

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60. Short SM, Short CM. (2008) Diversity of algal viruses in various North American freshwater 

environments. Aquatic Microbial Ecology (51): 13-21. 

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microbial mats. Environmental Biology (10): 950-966. 

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motif mediating K+/CI- cotransporter KCC2 constitutive endocytosis. Cellular Signaling (20): 

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Arabidopsis against oxidative stress. BMC Plant Biology (8): internet access. 

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of AP-2 reveals a general mechanism for receptors internalizing through the clathrin pathway. 

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molecular characterization of Cryptosporidium spp. in dairy calves from 11 farms in Prince Eward 

Island, Canada. Veterinary Parasitology. Electronic access. 

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African cichlid fish. Molecular Ecology 17(9): 2134-2148. 

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microsatellite loci for Percichthys Trucha. Molecular Ecology Ressources. Electronic access. 

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72. Darwish SA, Pan L, Ide C, Bede JC. (2008) Caterpillar-specific gene expression in the legume, 

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2007 

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Quantitative analysis of a proteome by N-terminal stable-isotope labelling of tryptic peptides. Rapid 

Communications in Mass Spectrometry 21: 2671-2679. 

2. Nyalendo C, Michaud M, Beaulieu E, Roghi C, Murphy G, Gingras D, Béliveau R (2007) Srcdependent 

Phosphorylation of Membrane Type I Matrix Metalloproteinase on Cytoplasmic Tyrosine 

573. J Biol Chem 282: 15690-15699. 

3. Colinet H, Nguyen TT, Cloutier C, Michaud D, Hance T (2007) Proteomic profiling of a parasitic wasp 

exposed to constant and fluctuating cold exposure. Insect Biochem Mol Biol 37: 1177-1188. 

4. Lahjouji K, Storms R, Xiao Z, Joung KB, Zheng Y, Powlowski J, Tsang A, Varin L (2007) Biochemical 

and molecular characterization of a cellobiohydrolase from Trametes versicolor. Appl Microbiol 

Biotechnol 75: 337-346. 

5. Codrington AM, Hales BF, Robaire B (2007) Exposure of male rats to cyclophosphamide alters the 

chromatin structure and basic proteome in spermatozoa. Hum Reprod 22: 1431-1442. 

6. Codrington AM, Hales BF, Robaire B (2007) Chronic Cyclophosphamide Exposure Alters the Profile 

of Rat Sperm Nuclear Matrix Proteins. Biol Reprod 77: 303-311. 

7. Zvereff V, Wang JC, Shun K, Lacoste J, Chevrette M. 2007 Colocalisation of CD9 and mortalin in 

CD9-induced mitotic catastrophe in human prostate cancer cells. Br J Cancer 97: 941-948. 

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differentially expressed genes. Int J Gynecol Cancer. 

10. Cody NA, Ouellet V, Manderson EN, Quinn MC, Filali-Mouhim A, Tellis P, Zietarska M, Provencher 

DM, Mes-Masson AM, Chevrette M, Tonin PN (2007) Transfer of chromosome 3 fragments 

suppresses tumorigenicity of an ovarian cancer cell line monoallelic for chromosome 3p. Oncogene 

26: 618–632. 

11. Maes OC, Xu S, Yu B, Chertkow HM, Wang E, Schipper HM (2007) Transcriptional profiling of 

Alzheimer blood mononuclear cells by microarray. Neurobiol Aging 28: 1795-1809. 

12. Zietarska M, Maugard CM, Filali-Mouhim A, Alam-Fahmy M, Tonin PN, Provencher DM, Mes-Masson 

AM (2007) Molecular description of a 3D in vitro model for the study of epithelial ovarian cancer 

(EOC). Mol Carcinog 46: 872-885. 

13. Puiffe ML, Le Page C, Filali-Mouhim A, Zietarska M, Ouellet V, Tonin PN, Chevrette M, Provencher 

DM, Mes-Masson AM (2007) Characterization of Ovarian Cancer Ascites on Cell Invasion, 

Proliferation, Spheroid Formation, and Gene Expression in an In Vitro Model of Epithelial Ovarian 

Cancer. Neoplasia 9: 820–829. 


14. Cory AT, Boyer A, Pilon N, Lussier JG, Silversides DW. Presumptive pre-sertoli cells express genes 

involved in cell proliferation and cell signalling during a critical window in early testis differentiation. 

Mol Reprod Dev. 2007 Apr 4. Expression arrays were done by the platform 

15. Yoon Ki Kim, Luc Furic, Marc Parisien, François Major, Luc DesGroseillers and Lynne E Maquat 

(2007) Staufen 1 regulates diverse classes of mammalian transcripts. EMBO J. 26:2670-2681. 

16. Canale-Zambrano JC, Poffenberger MC, Cory SM, Humes DG, Haston CK (2007) Intestinal 

phenotype of variable-weight cystic fibrosis knockout mice Am J Physiol Gastrointest Liver Physiol 

293: G222-G229. 

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HT, Nguyen TH, Nguyen NB, Moraes M, Mehra N, Schurr E, Abel L. Stepwise replication identifies a 

low-producing lymphotoxin-alpha allele as a major risk factor for early-onset leprosy. Nature Genetics 

2007 Apr;39 (4): 517-22. 

18. Vidal C, Galea R, Brincat M, Anastasi AX (2007) Linkage to chromosome 11p12 in two Maltese 

families with a highly penetrant form of osteoporosis. Eur J Hum Genet 15: 800-809. 

19. Taylor DM, Gibbs BF, Kabashi E, Minotti S, Durham HD, Agar JN (2007) Tryptophan 32 Potentiates 

Aggregation and Cytotoxicity of a Copper/Zinc Superoxide Dismutase Mutant Associated with 

Familial Amyotrophic Lateral Sclerosis. J Biol Chem 28216329-16335. 

20. Torrisani J, Unterberger A, Tendulkar SR, Shikimi K, Szyf M (2007) AUF1 Cell Cycle Variations 

Define Genomic DNA Methylation by Regulation of DNMT1 mRNA Stability. Mol Cell Biol 27: 395- 

410. 

21. Stuart LM, Boulais J, Charriere GM, Hennessy EJ, Brunet S, Jutras I, Goyette G, Rondeau C, Letarte 

S, Huang H, Ye P, Morales F, Kocks C, Bader JS, Desjardins M, Ezekowitz RA (2007) A system 

biology analysis of the Drosophila phagosome. Nature 445: 95-101. 

22. Uboha NV, Flajolet M, Nairn AC, Picciotto MR (2007) A calcium and calmodulin-dependent kinase Iα/ 

microtubule affinity regulating kinase 2 signaling cascade mediates calcium-dependent neurite 

outgrowth. J Neurosci 27: 4413-4423. 

23. Rossignol E, Mathieu J, Thiffault I, Tétreault M, Dicaire MJ, Chrestian N, Dupré N, Puymirat J, Brais B 

(2007) A novel founder SCN4A mutation causes painful cold-induced myotonia in French-Canadians. 

Neurology 69: 1937-1941. 

24. Jia X, Ebine N, Demonty I, Wang Y, Beech R, Muise V, Fortin MG, Jones PJ (2007) 

Hypocholesterolaemic effects of plant sterol analogues are independent of ABCG5 and ABCG8 

transporter expressions in hamsters. Br J Nutr 98: 550-555. 

25. Ahmad S, Dahllund L, Eriksson AB, Hellgren D, Karlsson U, Lund PE, Meijer IA, Meury L, Mills T, 

Moody A, Morinville A, Morten J, O'donnell D, Raynoschek C, Salter H, Rouleau GA, Krupp JJ (2007) 

A stop codon mutation in SCN9A causes lack of pain sensation. Hum Mol Genet 16: 2114-2121. 

26. Savitch LV, Subramaniam R, Allard GC, Singh J (2007) The GLK1 ‘regulon’ encodes disease 

defense related proteins and confers resistance to Fusarium graminearum in Arabidopsis. Biochem 

Biophys Res Commun 359: 234-238. 


27. Deval J, D'Abramo CM, Zhao Z, McCormick S, Coutsinos D, Hess S, Kvaratskhelia M, Götte M 

(2007) High Resolution Footprinting of the Hepatitis C Virus Polymerase NS5B in Complex with RNA. 

J Biol Chem 282: 16907-16916. 

28. Deval J, Powdrill MH, D'Abramo CM, Cellai L, Götte M (2007) Pyrophosphorolytic Excision of 

Nonobligate Chain Terminators by Hepatitis C Virus NS5B Polymerase. Microb Agents Chemother 

51: 2920-2928. 

29. Kgwatalala PM, Ibeagha-Awemu EM, Hayes JF, Zhao X (2007) Single nucleotide polymorphisms in 

the open reading frame of the stearoyl-CoA desaturase gene and resulting genetic variants in 

Canadian Holstein and Jersey cows. DNA Sequence 18: 357–362. 

30. Villemur R, Constant P, Gauthier A, Shareck M, Beaudet R (2007) Heterogeneity between 16S 

ribosomal RNA gene copies borne by one Desulfitobacterium strain is caused by different 100-200 bp 

insertions in the 5´ region. Can J Microbiol 53: 116-128. 

31. Coklin T, Farber J, Parrington L, Dixon B (2007) Prevalence and molecular characterization of Giardia 

duodenalis and Cryptosporidium spp. in dairy cattle in Ontario, Canada. Vet Parasitol 150: 297-305. 

32. Perreault NN, Andersen DT, Pollard WH, Greer CW, Whyte LG (2007) Characterization of the 

Prokaryotic Diversity in Cold Saline Perennial Springs of the Canadian High Arctic. Appl Environ 

Microbiol 73: 1532-1543.

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