2P5E: Crystal Structures of High Affinity Human T-Cell Receptors Bound to pMHC Reveal Native Diagonal Binding Geometry

PDB ID: 2P5EDownload
MMDB ID: 59237
PDB Deposition Date: 2007/3/15
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 1.89  Å
Source Organism:
synthetic construct▼
Similar Structures:
Biological Unit for 2P5E: pentameric; determined by author and by software (PISA,PQS)
Molecular Components in 2P5E
Label Count Molecule
Proteins (5 molecules)
1
HLA Class I Histocompatibility Antigen, A-2 Alpha Chain
Molecule annotation
1
Beta-2-microglobulin
Molecule annotation
1
Cancer/testis Antigen 1B
Molecule annotation
1
T-cell Receptor, Alpha Chain
Molecule annotation
1
Hypothetical Protein
Molecule annotation
Chemicals and Non-standard biopolymers (16 molecules)
1
8
GLYCEROLGLYCEROL
2
1
MAGNESIUM IONMAGNESIUM ION
3
5
SULFATE IONSULFATE ION
4
1
ISOPROPYL ALCOHOLISOPROPYL ALCOHOL
5
1
4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303