Kim Ekroos’ Post

Happy to share our new paper that is (finally) published in Molecular and Cellular Proteomics. This paper, from my time as a PhD candidate, allowed me to analyze Arabidopsis thaliana phosphoproteomic data generated by my amazing colleagues from The University of North Carolina at Chapel Hill and Iowa State University. By analyzing the significant differences between wild-type plants and G-signaling-deficient plants, we confirmed that the PP2A phosphatase subunit ATBα regulates G-signaling by controlling the phosphorylation-induced degradation of the seven-transmembrane regulator AtRGS1. I believe that this work and the dataset generated will greatly contribute to understanding the unconventional mechanisms of G-protein regulation in plants. Check the paper here: https://lnkd.in/d_aU_9Bi

Aya Nasr and I published our first paper about the in-vitro part of our PhD Project! We investigated the influence of excess salt on macrophage core functions. Next we will let you know what's happening in your gut and skin... https://lnkd.in/ek5gTwug

Check out our recently published paper!

A framework for the evaluation and reporting of incidental findings in clinical genomic testing | European Journal of Human Genetics (nature.com) Currently, there are no widely accepted recommendations in the genomics field guiding the return of incidental findings (IFs), defined here as unexpected results that are unrelated to the indication for testing. Consequently, reporting policies for IFs among laboratories offering genomic testing are variable and may lack transparency. Herein we describe a framework developed to guide the evaluation and return of IFs encountered in probands undergoing clinical genome sequencing (cGS). The framework prioritizes clinical significance and actionability of IFs and follows a stepwise approach with stopping points at which IFs may be recommended for return or not.