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KIR2DL3/CD158b2 Antibody (GL183), Novus Biologicals™

Name: KIR2DL3/CD158b2 Antibody (GL183), Novus Biologicals&trade;
Brand: Novus Biologicals
SKU: NB017750
Price: 204.00 USD

Mouse Monoclonal Antibody

Supplier: Novus Biologicals NB100658750.025MG

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Catalog No. NB017750

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Description

KIR2DL3/CD158b2 Monoclonal specifically detects KIR2DL3/CD158b2 in Human samples. It is validated for Flow Cytometry, Immunoprecipitation.

Specifications

Antigen	KIR2DL3/CD158b2
Classification	Monoclonal
Concentration	1 mg/mL
Dilution	Flow Cytometry 1:10-1:50, Immunoprecipitation 1:10-1:500
Gene Accession No.	P43628
Gene Symbols	KIR2DL3
Immunogen	NK cell clone E57
Quantity	0.025 mg
Research Discipline	Apoptosis
Gene ID (Entrez)	3804
Target Species	Human
Form	Purified

Applications	Flow Cytometry, Immunoprecipitation
Clone	GL183
Conjugate	Unconjugated
Formulation	PBS, 0.5% Bovine Serum Albumin with 0.09% Sodium Azide
Gene Alias	CD158 antigen-like family member B2, CD158b2 antigen, CD158B2CD158b, cl-6, killer cell immunoglobulin-like receptor 2DL3, killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3, Killer inhibitory receptor cl 2-3, KIR-023GB, KIRCL23, KIR-K7b, KIR-K7c, MGC129943, MHC class I NK cell receptor, natural killer associated transcript 2, natural killer cell inhibitory receptor KIR2DL3, Natural killer-associated transcript 2, NKAT, nkat2, NKAT-2, NKAT2a, NKAT2B, NKAT2GL183, NK-receptor, p58, p58 natural killer cell receptor clone CL-6, p58 NK receptor CL-6, p58.2 MHC class-I specific NK receptor, p58.2 MHC class-I-specific NK receptor
Host Species	Mouse
Purification Method	Protein A or G purified
Regulatory Status	RUO
Primary or Secondary	Primary
Test Specificity	NB100-65875 recognizes the human CD158b cell surface antigen, a 58kD glycoprotein expressed by a subset of NK cells (also known as p58.2 antigen). This antibody also recognizes a 50kD molecule, which is highly homologous to p58.2 in the extracellular domain, but has a shorter cytoplasmic tail. Both molecules are members of the newly described natural killer cell receptor family. CD158b functions as a receptor specific for HLA Class I molecules, including Cw3 and related HLA-C alleles. This antibody can restore the lysis by human NK clones of otherwise lysis protected targets expressing Cw3.
Content And Storage	Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Isotype	IgG1

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KIR2DL3/CD158b2 Antibody (GL183), Novus Biologicals™

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