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Abnova™ Human IL2 (NP_000577, 22 a.a. - 153 a.a.) Partial Recombinant Protein

Name: Abnova&trade; Human IL2 (NP_000577, 22 a.a. - 153 a.a.) Partial Recombinant Protein
Brand: Abnova&trade;
SKU: 89-948-788
Price: 771.00 USD

Used for Func, SDS-PAGE

Supplier: Abnova™ P3455

Catalog No. 89-948-788

$771.00 / Each of 1

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Description

The protein encoded by this gene is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli. [provided by RefSeq]

Sequence: MPTSSSTKKTQLQLEHLLLDLQMILNGINNYKNPKLTRMLTFKFYMPKKATELKHLQCLEEELKPLEEVLNLAQSKNFHLRPRDLISNINVIVLELKGSETTFMCEYADETATIVEFLNRWITFSQSIISTLT

Specifications

Accession Number	NP_000577
For Use With (Application)	Functional Study, SDS-PAGE
Gene ID (Entrez)	3558
Name	IL2 (Human) Recombinant Protein
Purification Method	Conventional Chromatography
Quantity	100 ug
Storage Requirements	Store at 4°C for 1-2 weeks. For long term storage store at -20°C or -80°C. Aliquot to avoid repeated freezing and thawing.
Gene Alias	IL-2/TCGF/lymphokine
Gene Symbol	IL2
Species	E. coli
Protein Tag	None
Form	Liquid

Concentration	0.5 mg/mL
Formulation	Liquid
Molecular Weight (g/mol)	15.4kDa
Preparation Method	Escherichia coli expression system
Quality Control Testing	Loading 3 ug protein in 15% SDS-PAGE
Immunogen	MPTSSSTKKTQLQLEHLLLDLQMILNGINNYKNPKLTRMLTFKFYMPKKATELKHLQCLEEELKPLEEVLNLAQSKNFHLRPRDLISNINVIVLELKGSETTFMCEYADETATIVEFLNRWITFSQSIISTLT
Regulatory Status	RUO
Common Name	IL2
Biological Activity	Measured in a cell proliferation assay using CTLL2 mouse cytotoxic T cells. The ED50 for this effect is < 1.5ng/mL.
Recombinant	Recombinant
Expression System	Escherichia coli expression system
Purity or Quality Grade	>95% by SDS-PAGE

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Abnova™ Human IL2 (NP_000577, 22 a.a. - 153 a.a.) Partial Recombinant Protein

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