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Abnova™ Human IL2 (NP_000577, 22 a.a. - 153 a.a.) Partial Recombinant Protein
Used for Func, SDS-PAGE
Supplier: Abnova™ P3455
Description
The protein encoded by this gene is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli. [provided by RefSeq]
Sequence: MPTSSSTKKTQLQLEHLLLDLQMILNGINNYKNPKLTRMLTFKFYMPKKATELKHLQCLEEELKPLEEVLNLAQSKNFHLRPRDLISNINVIVLELKGSETTFMCEYADETATIVEFLNRWITFSQSIISTLTSpecifications
NP_000577 | |
Functional Study, SDS-PAGE | |
3558 | |
IL2 (Human) Recombinant Protein | |
Conventional Chromatography | |
100 ug | |
Store at 4°C for 1-2 weeks. For long term storage store at -20°C or -80°C. Aliquot to avoid repeated freezing and thawing. | |
IL-2/TCGF/lymphokine | |
IL2 | |
E. coli | |
None | |
Liquid |
0.5 mg/mL | |
Liquid | |
15.4kDa | |
Escherichia coli expression system | |
Loading 3 ug protein in 15% SDS-PAGE | |
MPTSSSTKKTQLQLEHLLLDLQMILNGINNYKNPKLTRMLTFKFYMPKKATELKHLQCLEEELKPLEEVLNLAQSKNFHLRPRDLISNINVIVLELKGSETTFMCEYADETATIVEFLNRWITFSQSIISTLT | |
RUO | |
IL2 | |
Measured in a cell proliferation assay using CTLL2 mouse cytotoxic T cells. The ED50 for this effect is < 1.5ng/mL. | |
Recombinant | |
Escherichia coli expression system | |
>95% by SDS-PAGE |
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