Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
CHRNA7 (extracellular) Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Supplier: Thermo Scientific PA5107098
Description
Sequence homology: Cow: 93%; Human: 100%; Mouse: 100%; Rat: 100%
Chromosome 15 encodes over 700 genes and comprises nearly 3% of the human genome. CHRFAM7A, a fusion protein comprised of FAM7A and AChR alpha7, is encoded by the CHRFAM7A gene, which is located on a region of human chromosome 15 that is associated with several neuropsychiatric disorders, such as schizophrenia and bipolar affective disorder. CHRFAM7A, also known as D-10 or CHRNA7, is a 412 amino acid multi-pass membrane protein that belongs to the nicotinic acetylcholine receptor (nAChR) subfamily of ligand-gated ion channel proteins, a protein superfamily that mediates signal transmission at synapses. CHRFAM7A is expressed in the hippocampus. Alternative splicing of the CHRFAM7A gene produces two splice variants.
Specifications
| CHRNA7 (extracellular) | |
| Polyclonal | |
| Unconjugated | |
| CHRNA7 | |
| a7 nicotinic acetylcholine receptor; acetylcholine receptor; acetylcholine receptor alpha 7 neural; Acra7; alpha 7 neuronal nicotinic acetylcholine receptor; alpha7; alpha-7 nicotinic cholinergic receptor subunit; alpha7 nicotinic receptor; alpha7-nAChR; BTX; bungarotoxin alpha; C holinergic receptor nicotinic alpha polypeptide 7 (neuronal nicotinic acetycholine receptor alpha 7) (bungarotoxin alpha); C holinergic receptor, nicotinic, alpha polypeptide 7 (neuronal nicotinic acetycholine receptor alpha 7) (bungarotoxin alpha); cholinergic receptor; cholinergic receptor nicotinic alpha 7 subunit; cholinergic receptor, nicotinic alpha 7; cholinergic receptor, nicotinic, alpha 7 (neuronal); cholinergic receptor, nicotinic, alpha polypeptide 7; CHRFAM7A; Chrna7; CHRNA7-2; CHRNA7-DR1; D-10; nAchR; nAChR alpha7; NACHRA7; NARAD; neuronal acetylcholine receptor protein, alpha-7 chain; neuronal acetylcholine receptor subunit alpha-7; neuronal nicotinic acetycholine receptor alpha 7; nicotinic re | |
| Rabbit | |
| Protein A | |
| RUO | |
| 1139, 25302 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Western Blot | |
| 1 mg/mL | |
| PBS with 2% sucrose and 0.09% sodium azide; pH 7.4 | |
| P36544, Q05941 | |
| CHRNA7 | |
| Synthetic peptide located within the following region: QGEFQRKLYK ELVKNYNPLE RPVANDSQPL TVYFSLSLLQ IMDVDEKNQV | |
| 100 μL | |
| Primary | |
| Human, Rat | |
| Antibody | |
| IgG |
Provide Content Correction
We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.
Product Title
Spot an opportunity for improvement?
Provide Content Correction