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ABCB4 Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Supplier: Thermo Scientific PA5100194
Description
Antibody detects endogenous levels of total MDR3.
The membrane-associated protein encoded ABCB4 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This gene encodes a full transporter and member of the p-glycoprotein family of membrane proteins with phosphatidylcholine as its substrate. The function of this protein has not yet been determined; however, it may involve transport of phospholipids from liver hepatocytes into bile. Alternative splicing of this gene results in several products of undetermined function.Specifications
ABCB4 | |
Polyclonal | |
Unconjugated | |
ABCB4 | |
ABC20; ABC21; ABCB4; ATP binding cassette subfamily B member 4; ATP-binding cassette sub-family B (MDR/TAP) member 4 (P-glycoprotein 3/ multidrug resistance 2; ATP-binding cassette sub-family B (MDR/TAP) member 4 (P-glycoprotein 3/ multidrug resistance 2); ATP-binding cassette sub-family B member 4; ATP-binding cassette, subfamily B (MDR/TAP), member 4; ATP-binding cassette, sub-family B (MDR/TAP), member 4; ATP-binding cassette, sub-family B (MDR/TAP), member 4 (P-glycoprotein 3/ multidrug resistance 2); ATP-binding cassette, subfamily B, member 4; CD243; CLCS; GBD1; GP170; ICP3; MDR1; MDR2; mdr-2; MDR2/3; MDR3; MGC163296; Multidrug resistance protein 2; multidrug resistance protein 3; multiple drug resistance 3; P glycoprotein 2; P glycoprotein 3/multiple drug resistance 3; PFIC-3; P-glycoprotein 2; P-glycoprotein 3; P-glycoprotein 3/ multidrug resistance 2; P-glycoprotein-3/multiple drug resistance-3; P-GP; Pgp3; PGY1; Pgy2; Pgy-2; Pgy3; Phosphatidylcholine translocator ABCB4 | |
Rabbit | |
Affinity chromatography | |
RUO | |
18670, 5244 | |
-20°C | |
Liquid |
Immunocytochemistry, Western Blot | |
1 mg/mL | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 | |
P21439, P21440 | |
ABCB4 | |
A synthesized peptide derived from human ABCB4(Accession P21439), corresponding to amino acid residues C353-Y403. | |
100 μL | |
Primary | |
Human, Mouse | |
Antibody | |
IgG |
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