2000 Laureate
Current position
Group leader, CNRS Research Director (DR2), Director of BioCampus Montpellier, Head of the MGX-Montpellier GenomiX core NGS facility
Host Institution
Institut de Génomique Fonctionnelle, Montpellier, France
laurent.journot@igf.cnrs.fr
Parental genomic imprinting is an epigenetic mechanism of gene regulation. It is understood as a mechanism aimed at controlling the amount of maternal resources allocated to the offspring from conception to weaning. Laurent Journot is performing a holistic analysis of imprinted gene function to understand the role of these genes in embryonic development, cell differentiation, and tumorigenesis.
• 1981-1984, Undergraduate studies at the Ecole Normale Supérieure de Cachan, Cachan, France
• 1991, Ph.D. in Molecular Biology, University of Montpellier, France, Joël Bockaert’s Lab
• 1991-1993, Postdoctoral fellow at the Zentrum für Molekulare Biologie der Universität Heidelberg, Heidelberg, Germany, Peter H. Seeburg’s Lab.
• 1993, Appointed CNRS Staff Scientist, Centre de Pharmacologie-Endocrinologie, Montpellier, France
• 1998, Appointed CNRS Research Director, Group Leader, Institut de Génomique Fonctionnelle, Montpellier, France
• Award of the Ligue Nationale contre le Cancer, 1997
• CNRS Bronze Medal, 1995
• EMBO Fellow, 1991
Zac1 regulates the differentiation and migration of neocortical neurons via Pac1.
Sep 2015, J. Neurosci.
H19 acts as a trans regulator of the imprinted gene network controlling growth in mice.
Oct 2009, Development