t(11;14)(q13;q32)

Description

Description: t(11;14)(q13;q32) is a translocation event involving chromosome 11 and 14. In particular, the segment from 11q13 to 11qter replaces the segment from 14q32 to 14qter and vice-versa. This is frequently found in multiple myeloma, chronic lymphoblastic leukemia, B-cell prolymphocytic Leukemia and mantle cell lymphoma.


Source	This text was researched, composed and written by the MarkerDB curation team. Source information was obtained from the Atlas of Genetics and Cytogenetics in Oncology and Haematology. Last update: Aug. 2020.

Indications

Specific Condition:	Multiple Myeloma

General Condition:	Cancer
Associated Gene(s):	IGH CCND1
Age:	Elderly( >65 yrs old)
Sex:	Both
Reference:	Huret, JL t(11;14)(q13;q32) Atlas Genet Cytogenet Oncol Haematol. 1998;2(4):129-131.

Specific Condition:	Chronic Lymphocytic Leukemia

General Condition:	Immune System Disorder Cancer Hematological or Lymphatic System Disorder
Associated Gene(s):	IGH CCND1
Age:	Elderly( >65 yrs old)
Sex:	Both
Reference:	Huret, JL t(11;14)(q13;q32) Atlas Genet Cytogenet Oncol Haematol. 1998;2(4):129-131.

Specific Condition:	Mantle Cell Lymphoma

General Condition:	Cancer
Associated Gene(s):	IGH CCND1
Age:	Elderly( >65 yrs old)
Sex:	Both
Reference:	Huret, JL t(11;14)(q13;q32) Atlas Genet Cytogenet Oncol Haematol. 1998;2(4):129-131.

MDB00005083


Creation Date:	2020-08-01
Update Date:	2020-08-15

Idiogram

Image